Anti-AIPL1抗体(ab79039)
Key features and details
- Rabbit polyclonal to AIPL1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-AIPL1抗体
参阅全部 AIPL1 一抗 -
描述
兔多克隆抗体to AIPL1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
A 17 amino acid synthetic peptide near the carboxy terminus of human AIPL1 (NP_055151).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab79039 was purified by affinity chromatography via a peptide column -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab79039于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.
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| ICC/IF |
Use a concentration of 20 µg/ml.
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| IHC-P |
Use at an assay dependent concentration.
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| 说明 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa. |
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ICC/IF
Use a concentration of 20 µg/ml. |
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IHC-P
Use at an assay dependent concentration. |
靶标
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功能
May be important in protein trafficking and/or protein folding and stabilization. -
组织特异性
Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina. -
疾病相关
Defects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children. -
序列相似性
Contains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats. -
细胞定位
Cytoplasm. Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 23746 Human
- Omim: 604392 Human
- SwissProt: Q9NZN9 Human
- Unigene: 279887 Human
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别名
- A930007I01Rik antibody
- Aipl1 antibody
- AIPL1_HUMAN antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-AIPL1 antibody (ab79039)
Immunofluorescence of AIPL1 in Human brain tissue with ab79039 at 20 ug/mL.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIPL1 antibody (ab79039)Immunohistochemistry of Human brain tisue using ab79039 at 2.5 μg/ml.
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Western blot - Anti-AIPL1 antibody (ab79039)Lane 1 : Anti-AIPL1 antibody (ab79039) at 1 µg/ml
Lane 2 : Anti-AIPL1 antibody (ab79039) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 44 kDa
Observed band size: 36 kDa why is the actual band size different from the predicted?
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab79039 被引用在 1 文献中.
- He J et al. SIPL1, Regulated by MAZ, Promotes Tumor Progression and Predicts Poor Survival in Human Triple-Negative Breast Cancer. Front Oncol 11:766790 (2021). PubMed: 34976812