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Anti-AIM2抗体(ab119791)

Submit a review Q&A (1)References (6)
Western blot - Anti-AIM2 antibody (ab119791)

    Key features and details

    • Rabbit polyclonal to AIM2
    • Suitable for: WB
    • Reacts with: Mouse, Human
    • Isotype: IgG

    概述

    • 产品名称

      Anti-AIM2抗体
      参阅全部 AIM2 一抗

    • 描述

      兔多克隆抗体to AIM2

    • 宿主

      Rabbit

    • 经测试应用

      适用于: WBmore details

    • 种属反应性

      与反应: Mouse, Human
      预测可用于: Rat

    • 免疫原

      Synthetic peptide conjugated to a carrier protein, corresponding to residues in the N terminal of Human AIM2.

    • 阳性对照

      • Jurkat whole cell lysate (ab7899); Mouse macrophages treated with IFN gamma and LPS.

    • 常规说明

      Do not aliquot.

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab119791于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
    说明
    WB
    1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

    靶标

    图片

    • Western blot - Anti-AIM2 antibody (ab119791)
      Western blot - Anti-AIM2 antibody (ab119791)
      All lanes : Anti-AIM2 antibody (ab119791) at 1/1000 dilution

      Lane 1 : Human Jurkat cells
      Lane 2 : Mouse macrophages, untreated
      Lane 3 : Mouse macrophages, treated with IFN gamma (10 ng/ml) and LPS (1mg/ml) for 12 hr

      Lysates/proteins at 20 µg per lane.

      Predicted band size: 39 kDa

    文献 (6)

    发表研究结果有使用 ab119791？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab119791 被引用在 6 文献中.

    • Zhou Q  et al. Pseudorabies Virus Infection Activates the TLR-NF-κB Axis and AIM2 Inflammasome To Enhance Inflammatory Responses in Mice. J Virol 97:e0000323 (2023). PubMed: 36877049
    • Jarabicová I  et al. Analysis of necroptosis and its association with pyroptosis in organ damage in experimental pulmonary arterial hypertension. J Cell Mol Med 26:2633-2645 (2022). PubMed: 35393789
    • Chen J  et al. Atorvastatin ameliorates early brain injury after subarachnoid hemorrhage via inhibition of pyroptosis and neuroinflammation. J Cell Physiol 236:6920-6931 (2021). PubMed: 33792028
    • Lee S  et al. AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence. Nature 597:415-419 (2021). PubMed: 34471287
    • Fidler TP  et al. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature 592:296-301 (2021). PubMed: 33731931
    • Li Y  et al. Sevoflurane attenuates cardiomyocyte apoptosis by mediating the miR-219a/AIM2/TLR4/MyD88 axis in myocardial ischemia/reperfusion injury in mice. Cell Cycle 19:1665-1676 (2020). PubMed: 32449438

    客户评价及客户问答

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    Question

    ab119791 detects no difference between my WT and KO samples

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    Answer

    Thank you for contacting us.

    Your credit note ID is ***.

    I am sorry that this antibody did not perform as stated on the datasheet. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact our accounting department so that we may gather the correct information needed for the refund. To avoid confusion, please ensure your accounts department is aware of how the credit note is being used.

    Our accounting department can be contacted by email at us.credits@abcam.com or by telephone using the information at the Contact Us link in the top right corner of our website. Please refer to the credit note ID in any correspondence with our accounting department.

    The credit note ID is for your reference only and does not automatically guarantee the credit.

    I hope this experience will not prevent you from purchasing other products from us in the future. Our Scientific Support team is always at your service, should you require further expert advice.

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