Anti-AIFM3抗体(ab106359)
Key features and details
- Rabbit polyclonal to AIFM3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-AIFM3抗体 -
描述
兔多克隆抗体to AIFM3 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human AIFM3 (N terminal). 16 amino acid peptide
Database link: Q96NN9 -
阳性对照
- Human tissue lysates and Human brain tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 2.68% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106359于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.
|
|
| IHC-P |
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa. |
|
IHC-P
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. |
靶标
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功能
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. -
组织特异性
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level). -
序列相似性
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain. -
结构域
The Rieske domain induces apoptosis. -
细胞定位
Mitochondrion. Does not translocate to the nucleus upon induction of apoptosis. - Information by UniProt
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数据库链接
- Entrez Gene: 150209 Human
- SwissProt: Q96NN9 Human
- Unigene: 723246 Human
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别名
- AIFL antibody
- Aifm3 antibody
- AIFM3_HUMAN antibody
see all
图片
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Western blot - Anti-AIFM3 antibody (ab106359)Lane 1 : Anti-AIFM3 antibody (ab106359) at 1 µg/ml
Lane 2 : Anti-AIFM3 antibody (ab106359) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 67 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIFM3 antibody (ab106359)Immunohistochemical staining of human brain tissue using ab106359 at 2.5 µg -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AIFM3 antibody (ab106359)Immunohistochemistry of AIFM3 in Human brain tissue with ab106359 at 20 ug/mL.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab106359 被引用在 1 文献中.
- Araujo AN et al. Comprehensive Assessment of Copy Number Alterations Uncovers Recurrent AIFM3 and DLK1 Copy Gain in Medullary Thyroid Carcinoma. Cancers (Basel) 13:N/A (2021). PubMed: 33435319