Anti-Agpat2抗体(ab124380)
Key features and details
- Rabbit polyclonal to Agpat2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Agpat2抗体
参阅全部 Agpat2 一抗 -
描述
兔多克隆抗体to Agpat2 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat
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免疫原
Recombinant fragment, corresponding to amino acids 142-279 of Human Agpat2 (BC019292).
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阳性对照
- Human fetal heart tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Add 200ul sterile distilled water -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab123380 is purified by a protein affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab124380于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100 - 1/500.
|
| 说明 |
|---|
|
IHC-P
1/100 - 1/500. |
靶标
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功能
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. -
组织特异性
Expressed predominantly in heart and liver. -
通路
Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3. -
疾病相关
Defects in AGPAT2 are the cause of congenital generalized lipodystrophy type 1 (CGL1) [MIM:608594]; also known as Berardinelli-Seip congenital lipodystrophy type 1 (BSCL1) or Berardinelli-Seip syndrome. CGL1 is an autosomal recessive disorder characterized by marked paucity of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes. -
序列相似性
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. -
结构域
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 10555 Human
- Entrez Gene: 67512 Mouse
- Entrez Gene: 311821 Rat
- Omim: 603100 Human
- SwissProt: O15120 Human
- SwissProt: Q8K3K7 Mouse
- Unigene: 320151 Human
- Unigene: 24244 Mouse
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别名
- 1 acyl sn glycerol 3 phosphate acyltransferase beta antibody
- 1 acylglycerol 3 phosphate O acyltransferase 2 antibody
- 1 AGP acyltransferase 2 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Agpat2 antibody (ab124380)ab124380, at 1/100 dilution, staining Agpat2 in formalin-fixed, paraffin-embedded Human fetal heart tissue by Immunohistochemistry.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab124380 尚未被引用在任何文献中。