AB1253

Agarose Anti-Myc tag 抗体

Name: Agarose Anti-Myc tag抗体 (ab1253)| Abcam中文官网
Brand: Abcam Limited
SKU: AB1253
Rating: 4 (3 reviews)

Agarose Anti-Myc tag antibody

(3 Reviews)

(14 Publications)

Goat Polyclonal C-Myc/MYC antibody - conjugated to Agarose. Suitable for IP and reacts with Tag samples. Cited in 14 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human MYC conjugated to Keyhole Limpet Haemocyanin.

查看别名

BHLHE39, MYC, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, Proto-oncogene c-Myc, Transcription factor p64, bHLHe39

关键信息

宿主种属

Goat

克隆

Polyclonal

亚型

IgG

偶联物

Agarose

激发波长/发射波长

不含载体蛋白

应用

applications

免疫原

Native Full Length Protein corresponding to Human MYC conjugated to Keyhole Limpet Haemocyanin.

P01106

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Tag": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "20-40 µg/mL", "IP-species-notes": "<p>Use at a concentration of 20 - 40 µg/ml. Use at a concentration of 15-25 ul of gel slurry per 0.1 to 1 mg of protein lysate or extract.</p>" } } }

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产品详情

Affinity purified antibodies were coupled to agarose beads using a cyanogen bromide method.

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 6.8 - 7.4 Preservative: 0.1% Sodium azide Constituents: 0.58% Sodium chloride, 0.0268% PBS

运输条件

Blue Ice

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed : 24940000, PubMed : 25956029). Activates the transcription of growth-related genes (PubMed : 24940000, PubMed : 25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed : 24940000, PubMed : 25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed : 20010808).

See full target information MYC

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文献 (14)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 13:3084 PubMed35654893

2022

Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes.

Applications

Unspecified application

Species

Unspecified reactive species

Caroline E Dewar,Silke Oeljeklaus,Jan Mani,Wignand W D Mühlhäuser,Corinne von Känel,Johannes Zimmermann,Torsten Ochsenreiter,Bettina Warscheid,André Schneider

Diabetes 71:1246-1260 PubMed35377441

2022

DOC2b Enhances β-Cell Function via a Novel Tyrosine Phosphorylation-Dependent Mechanism.

Applications

Unspecified application

Species

Unspecified reactive species

Diti Chatterjee Bhowmick,Arianne Aslamy,Supriyo Bhattacharya,Eunjin Oh,Miwon Ahn,Debbie C Thurmond

NPJ Parkinson's disease 6:34 PubMed33298952

2020

Acquired dysregulation of dopamine homeostasis reproduces features of Parkinson's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Meghan L Bucher,Caitlyn W Barrett,Connor J Moon,Amanda D Mortimer,Edward A Burton,J Timothy Greenamyre,Teresa G Hastings

The Journal of biological chemistry 295:18343-18354 PubMed33122197

2020

PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS-driven cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Zhangsen Huang,Mingzhu Liu,Donghe Li,Yun Tan,Ruihong Zhang,Zhizhou Xia,Peihong Wang,Bo Jiao,Ping Liu,Ruibao Ren

PLoS genetics 16:e1008820 PubMed32750048

2020

DAnkrd49 and Bdbt act via Casein kinase Iε to regulate planar polarity in Drosophila.

Applications

Unspecified application

Species

Unspecified reactive species

Helen Strutt,David Strutt

Neoplasia (New York, N.Y.) 21:494-503 PubMed30986748

2019

C-terminal α Domain of p63 Binds to p300 to Coactivate β-Catenin.

Applications

Unspecified application

Species

Unspecified reactive species

Iyoko Katoh,Yojiro Maehata,Kohji Moriishi,Ryu-Ichiro Hata,Shun-Ichi Kurata

Biochemical and biophysical research communication 447:292-8 PubMed24727455

2014

Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Liquan Cai,Dan Wang,Alfred L Fisher,Zhou Wang

PLoS genetics 9:e1003545 PubMed23825959

2013

Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.

Applications

Species

Unspecified reactive species

Jesús A Carballo,Silvia Panizza,Maria Elisabetta Serrentino,Anthony L Johnson,Marco Geymonat,Valérie Borde,Franz Klein,Rita S Cha

Development (Cambridge, England) 140:1045-54 PubMed23364328

2013

The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2.

Applications

Species

Unspecified reactive species

Samantha J Warrington,Helen Strutt,David Strutt

American journal of human genetics 91:520-6 PubMed22958902

2012

Loss of SUFU function in familial multiple meningioma.

Applications

Unspecified application

Species

Unspecified reactive species

Mervi Aavikko,Song-Ping Li,Silva Saarinen,Pia Alhopuro,Eevi Kaasinen,Ekaterina Morgunova,Yilong Li,Kari Vesanen,Miriam J Smith,D Gareth R Evans,Minna Pöyhönen,Anne Kiuru,Anssi Auvinen,Lauri A Aaltonen,Jussi Taipale,Pia Vahteristo

View all publications

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Agarose Anti-Myc tag 抗体

Agarose Anti-Myc tag antibody

关键信息

宿主种属

克隆

亚型

偶联物

激发波长/发射波长

不含载体蛋白

应用

免疫原