JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB201083

Anti-ADAMTS7抗体

Anti-ADAMTS7 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal ADAMTS7 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human A disintegrin and metalloproteinase with thrombospondin motifs 7 aa 150-250.

查看别名

A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAM-TS 7, ADAM-TS7, ADAMTS-7, COMPase, ADAMTS7

1 Images
Western blot - Anti-ADAMTS7 antibody (AB201083)
  • WB

Supplier Data

Western blot - Anti-ADAMTS7 antibody (AB201083)

All lanes:

Western blot - Anti-ADAMTS7 antibody (ab201083)

Lane 1:

HEK293T whole cell lysate

Lane 2:

Mouse Raw 264.7 whole cell lysate

Lane 3:

Rat H9C2 whole cell lysate

Predicted band size: 184 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Mouse, Rat, Human

应用

WB

applications

免疫原

Synthetic Peptide within Human A disintegrin and metalloproteinase with thrombospondin motifs 7 aa 150-250. The exact immunogen used to generate this antibody is proprietary information.

Q9UKP4

style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
纯化说明
ab201083 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
存储溶液
pH: 7.3 Preservative: 0.05% Sodium azide Constituents: PBS
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
style
left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ADAMTS7 also known as ADAM Metallopeptidase with Thrombospondin Type 1 Motif 7 is an enzyme with a molecular mass of approximately 180 kDa. This protein is part of the ADAMTS family characterized by a disintegrin and metalloproteinase with thrombospondin motifs. ADAMTS7 is expressed mainly in the human kidney liver and skeletal muscle tissues. This protein plays a significant role in the degradation and remodeling of the extracellular matrix mediating processes such as protein processing and extracellular matrix assembly.
Biological function summary

ADAMTS7 functions as an important regulatory enzyme involved in the processing of cartilage oligomeric matrix protein (COMP). This process impacts the integrity and function of cartilage suggesting its vital role in maintaining cartilage homeostasis. Though it does not form part of a larger complex ADAMTS7 interacts closely with extracellular matrix components modulating cellular processes connected to tissue organization and structural integrity.

Pathways

ADAMTS7 is integral to the extracellular matrix organization pathway impacting its degradation and synthesis. It is also associated with the focal adhesion pathway which is critical for cell adhesion migration and signal transduction. In these pathways ADAMTS7 acts alongside proteins such as integrins and other matrix metalloproteinases coordinating cellular responses to mechanical and chemical stimuli through direct protein interactions.

ADAMTS7 has a connection to atherosclerosis and osteoarthritis. In atherosclerosis ADAMTS7 influences the remodeling of vascular tissues with effects on arterial stiffness and plaque stability. It interacts with proteins like low-density lipoprotein receptor-related protein 1 (LRP1) affecting lipid accumulation and inflammatory responses. In osteoarthritis ADAMTS7 contributes to cartilage degradation linking with other matrix-degrading enzymes to influence the progression of joint degeneration and inflammation.
style
left-column
style
left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

靶点信息

Metalloprotease that may play a role in the degradation of COMP.
See full target information A disintegrin and metalloproteinase with thrombospondin motifs 7
style
left-column

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 13:862085 PubMed35370630

2022

Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases.

Applications

Unspecified application

Species

Unspecified reactive species

Juan M Suárez-Rivero,Carmen J Pastor-Maldonado,Ana Romero-González,David Gómez-Fernandez,Suleva Povea-Cabello,Mónica Álvarez-Córdoba,Irene Villalón-García,Marta Talaverón-Rey,Alejandra Suárez-Carrillo,Manuel Munuera-Cabeza,José A Sánchez-Alcázar
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB203027

Anti-ADAMTS7 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ADAMTS7 antibody (AB203027)

  • 4
  • 1
Primary Antibodies

AB45044

Anti-ADAMTS7 antibody

Western blot - Anti-ADAMTS7 antibody (AB45044)

  • 0
  • 0
Primary Antibodies

AB28557

Anti-ADAMTS7 antibody

  • 4
  • 1
Primary Antibodies

AB222383

Anti-ADAMTS7 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ADAMTS7 antibody (AB222383)

  • 0
  • 0

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB41037

Anti-ADAMTS5 antibody

Western blot - Anti-ADAMTS5 antibody (AB41037)

  • 4
  • 9
Primary Antibodies

AB314857

Anti-ADAMTS4 antibody [EPR24094-30] - BSA and Azide free

RabMAb|Recombinant

Western blot - Anti-ADAMTS4 antibody [EPR24094-30] - BSA and Azide free (AB314857)

  • 0
  • 0
Primary Antibodies

AB3778

Anti-Aggrecan antibody [6-B-4]

BOND RX™ Validated|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Aggrecan antibody [6-B-4] (AB3778)

  • 4
  • 7

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com