Anti-ADAM23抗体(ab126275)
Key features and details
- Rabbit polyclonal to ADAM23
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ADAM23抗体
参阅全部 ADAM23 一抗 -
描述
兔多克隆抗体to ADAM23 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow
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免疫原
Recombinant fragment, corresponding to a region within amino acids 139-414 of Human ADAM23 (O75077).
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阳性对照
- 293T, A431, Jurkat and Raji whole cell lysates.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab126275 is purified by antigen-affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab126275于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 92 kDa.
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| 说明 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 92 kDa. |
靶标
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相关性
ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. -
细胞定位
Single pass type I membrane protein. 3 isoforms produced by alternative splicing, gamma isoform is secreted. -
数据库链接
- Entrez Gene: 531241 Cow
- Entrez Gene: 8745 Human
- Entrez Gene: 23792 Mouse
- Entrez Gene: 301460 Rat
- Omim: 603710 Human
- SwissProt: O75077 Human
- SwissProt: Q9R1V7 Mouse
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别名
- A disintegrin and metalloproteinase domain 23 antibody
- ADAM metallopeptidase domain 23 antibody
- Disintegrin and metalloproteinase domain containing protein 23 antibody
see all
图片
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Western blot - Anti-ADAM23 antibody (ab126275)Anti-ADAM23 antibody (ab126275) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg
Predicted band size: 92 kDa
7.5% SDS-PAGE.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab126275 被引用在 1 文献中.
- Chen C et al. Mechanism and Role of the Neuropeptide LGI1 Receptor ADAM23 in Regulating Biomarkers of Ferroptosis and Progression of Esophageal Cancer. Dis Markers 2021:9227897 (2021). PubMed: 35003396