Anti-Activin Receptor Type IIA/ACVR2A抗体[MM0058-6J16] (ab78412)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)](https://www.abcam.cn/ps/products/78/ab78412/Images/Activin-Receptor-Type-IIA-Primary-antibodies-ab78412-1.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)")
Key features and details
- Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA/ACVR2A
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2
概述
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产品名称
Anti-Activin Receptor Type IIA/ACVR2A抗体[MM0058-6J16]
参阅全部 Activin Receptor Type IIA/ACVR2A 一抗 -
描述
小鼠单克隆抗体[MM0058-6J16] to Activin Receptor Type IIA/ACVR2A -
宿主
Mouse -
特异性
Specific for human Activin RIIA. No cross reactivity was found to hActivin RI and RIIB. -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Recombinant fragment corresponding to Activin Receptor Type IIA/ACVR2A.
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阳性对照
- IHC-P: Human placenta tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MM0058-6J16 -
同种型
IgG2 -
研究领域
相关产品
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Compatible Secondaries
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab78412于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/100.
|
| 说明 |
|---|
|
IHC-P
1/50 - 1/100. |
靶标
-
功能
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. -
序列相似性
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 92 Human
- Entrez Gene: 11480 Mouse
- Omim: 102581 Human
- SwissProt: P27037 Human
- SwissProt: P27038 Mouse
- Unigene: 470174 Human
- Unigene: 314338 Mouse
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别名
- Activin A receptor type IIA antibody
- Activin receptor type 2A antibody
- Activin receptor type IIA antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16] (ab78412)
ab78412 at 1/100 dilution staining Activin Receptor Type IIA/ACVR2A in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin embedded sections).
数据表及文件
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Datasheet download
文献 (1)
ab78412 被引用在 1 文献中.
- Lin TT et al. Follicular localization of growth differentiation factor 8 and its receptors in normal and polycystic ovary syndrome ovaries. Biol Reprod 98:683-694 (2018). PubMed: 29409020
