Anti-ABIN3抗体(ab113748)
Key features and details
- Rabbit polyclonal to ABIN3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ABIN3抗体
参阅全部 ABIN3 一抗 -
描述
兔多克隆抗体to ABIN3 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse
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免疫原
Synthetic peptide corresponding to Human ABIN3 (C terminal) conjugated to keyhole limpet haemocyanin.
Database link: Q96KP6 -
阳性对照
- IHC-P: Human adrenal tissue WB: Human spleen tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab113748于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
|
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| IHC-P |
Use a concentration of 5 µg/ml.
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| 说明 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa. |
|
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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相关性
ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3. -
细胞定位
Cytoplasmic and Nuclear (based on other ABIN family members). -
数据库链接
- Entrez Gene: 79931 Human
- Entrez Gene: 414084 Mouse
- Omim: 608019 Human
- SwissProt: Q96KP6 Human
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别名
- A20 binding inhibitor of NF kappa B activation 3 antibody
- ABIN 3 antibody
- ABIN 3 beta antibody
see all
图片
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Western blot - Anti-ABIN3 antibody (ab113748)All lanes : Anti-ABIN3 antibody (ab113748) at 1 µg/ml
Lane 1 : Human spleen tissue lysate
Lane 2 : Human spleen tissue lysate with blocking peptide
Predicted band size: 38 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABIN3 antibody (ab113748)ab113748, at 5 µg/ml, staining ABIN3 in formalin fixed, paraffin embedded, Human adrenal tissue by Immunohistochemistry
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab113748 被引用在 2 文献中.
- Wang X et al. The Imbalance of Mitochondrial Homeostasis of Peripheral Blood-Derived Macrophages Mediated by MAFLD May Impair the Walking Ability of Elderly Patients with Osteopenia. Oxid Med Cell Longev 2022:5210870 (2022). PubMed: 35368864
- Liu D et al. TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation. Cell Metab 31:726-740.e8 (2020). PubMed: 32268115