Anti-ABCF1抗体[ABC5H06] (ab50976)
Key features and details
- Mouse monoclonal [ABC5H06] to ABCF1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-ABCF1抗体[ABC5H06]
参阅全部 ABCF1 一抗 -
描述
小鼠单克隆抗体[ABC5H06] to ABCF1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant human ABCF1 fragment
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 0.316% Tris HCl, 1% BSA, 1.16% Sodium chloride -
Concentration information loading...
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纯度
Tissue culture supernatant -
纯化说明
Concentrated and dialyzed culture medium (protein free medium) of hybridoma -
克隆
单克隆 -
克隆编号
ABC5H06 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab50976于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (1) |
1/100. Detects a band of approximately 85 kDa (predicted molecular weight: 96 kDa).
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说明 |
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WB
1/100. Detects a band of approximately 85 kDa (predicted molecular weight: 96 kDa). |
靶标
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功能
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. -
组织特异性
Ubiquitous. -
序列相似性
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Contains 2 ABC transporter domains. -
翻译后修饰
Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes. -
细胞定位
Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope. - Information by UniProt
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数据库链接
- Entrez Gene: 23 Human
- Omim: 603429 Human
- SwissProt: Q8NE71 Human
- Unigene: 655285 Human
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别名
- ABC27 antibody
- ABC50 antibody
- ABCF1 antibody
see all
图片
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Anti-ABCF1 antibody [ABC5H06] (ab50976) at 1/100 dilution + RIPA lysate of HeLa cells at 500 µg
Secondary
Anti-mouse IgG at 1/1000 dilution
Developed using the ECL technique.
Predicted band size: 96 kDa
Observed band size: 85 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (1)
ab50976 被引用在 1 文献中.
- Pechenino AS et al. Impact of aging vs. estrogen loss on cardiac gene expression: estrogen replacement and inflammation. Physiol Genomics 43:1065-73 (2011). WB ; Rat . PubMed: 21750230