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Cardiovascular Hypoxia Hypoxia-Regulated

Anti-ABCB6/PRP抗体(ab47837)

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Western blot - Anti-ABCB6/PRP antibody (ab47837)

    Key features and details

    • Rabbit polyclonal to ABCB6/PRP
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

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    概述

    • 产品名称

      Anti-ABCB6/PRP抗体
      参阅全部 ABCB6/PRP 一抗
    • 描述

      兔多克隆抗体to ABCB6/PRP
    • 宿主

      Rabbit
    • 经测试应用

      适用于: WBmore details
    • 种属反应性

      与反应: Human
      预测可用于: Mouse, Rat
    • 免疫原

      Synthetic peptide corresponding to Human ABCB6/PRP aa 440-455 (internal sequence).
      Sequence:

      RAMNTQENATRARAVD

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • 阳性对照

      • KB cells transfected with the ABCB6/PRP protein.
    • 常规说明

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    性能

    • 形式

      Liquid
    • 存放说明

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    • 存储溶液

      Preservative: 0.01% Sodium azide
      Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride
    • Concentration information loading...
    • 纯度

      Immunogen affinity purified
    • 克隆

      多克隆
    • 同种型

      IgG
    • 研究领域

      • Cardiovascular
      • Hypoxia
      • Hypoxia-Regulated
      • Signal Transduction
      • Metabolism
      • Mitochondrial
      • Cancer
      • Drug resistance
      • P glycoproteins
      • Metabolism
      • Pathways and Processes
      • Mitochondrial Metabolism
      • Mitochondrial markers
      • Metabolism
      • Pathways and Processes
      • Metabolism processes
      • Hypoxia
      • Metabolism
      • Types of disease
      • Cancer

    相关产品

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Recombinant Protein

      • Recombinant Human ABCB6/PRP protein (ab127452)

    应用

    The Abpromise guarantee

    Abpromise™承诺保证使用ab47837于以下的经测试应用

    “应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

    应用 Ab评论 说明
    WB
    说明
    应用说明
    ELISA: 1/40000 - 1/200000.
    IF (microscopy): Use at an assay dependent dilution.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    靶标

    • 功能

      Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
    • 组织特异性

      Widely expressed. Highest expression in heart and skeletal muscles.
    • 序列相似性

      Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
      Contains 1 ABC transmembrane type-1 domain.
      Contains 1 ABC transporter domain.
    • 发展阶段

      Highly expressed in fetal liver.
    • 细胞定位

      Mitochondrion outer membrane.
    • Target information above from: UniProt accession Q9NP58 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • 数据库链接

      • Entrez Gene: 10058 Human
      • Entrez Gene: 74104 Mouse
      • Entrez Gene: 140669 Rat
      • Omim: 605452 Human
      • SwissProt: Q9NP58 Human
      • SwissProt: Q9DC29 Mouse
      • SwissProt: O70595 Rat
      • Unigene: 107911 Human
      • Unigene: 28663 Mouse
      • Unigene: 54408 Rat
      see all
    • 别名

      • ABC antibody
      • ABC transporter umat antibody
      • ABC14 antibody
      • Abcb6 antibody
      • ABCB6_HUMAN antibody
      • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
      • ATP-binding cassette half-transporter antibody
      • ATP-binding cassette sub-family B member 6 antibody
      • ATP-binding cassette sub-family B member 6, mitochondrial antibody
      • DUH3 antibody
      • LAN antibody
      • MCOPCB7 antibody
      • Mitochondrial ABC transporter 3 antibody
      • mitochondrial antibody
      • Mt ABC transporter 3 antibody
      • Mt-ABC transporter 3 antibody
      • MTABC3 antibody
      • P glycoprotein related protein antibody
      • P-glycoprotein-related protein antibody
      • PRP antibody
      • Ubiquitously expressed mammalian ABC half transporter antibody
      • Ubiquitously-expressed mammalian ABC half transporter antibody
      • UMAT antibody
      see all

    图片

    • Western blot - Anti-ABCB6/PRP antibody (ab47837)
      Western blot - Anti-ABCB6/PRP antibody (ab47837)
      All lanes : Anti-ABCB6/PRP antibody (ab47837) at 1/1400 dilution

      Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6/PRP protein
      Lane 2 : KB cell lysate without a vector insert

      Predicted band size: 93 kDa
      Observed band size: 104 kDa why is the actual band size different from the predicted?
      Additional bands at: 79 kDa (possible truncated form)

    实验方案

    • Western blot protocols

    Click here to view the general protocols

    数据表及文件

    • Datasheet download

      Download

    文献 (0)

    发表研究结果有使用 ab47837?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab47837 尚未被引用在任何文献中。

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