Anti-5HT3B receptor抗体(ab115023)
Key features and details
- Goat polyclonal to 5HT3B receptor
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-5HT3B receptor抗体
参阅全部 5HT3B receptor 一抗 -
描述
山羊多克隆抗体to 5HT3B receptor -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide corresponding to Rat 5HT3B receptor aa 150-250 (internal sequence).
Database link: NP_071525.1 -
阳性对照
- Rat brain lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab115023 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115023于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
1 hour primary incubation is recommended for this product. |
| 说明 |
|---|
|
WB
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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功能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. -
组织特异性
Expressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta. -
序列相似性
Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily. -
翻译后修饰
N-glycosylation required for membrane localization. -
细胞定位
Cell membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A. - Information by UniProt
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数据库链接
- Entrez Gene: 58963 Rat
- SwissProt: Q9JJ16 Rat
- Unigene: 87106 Rat
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别名
- 5 HT3 B antibody
- 5 HT3B antibody
- 5 HTR3B antibody
see all
图片
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Western blot - Anti-5HT3B receptor antibody (ab115023)Anti-5HT3B receptor antibody (ab115023) at 0.1 µg/ml + Rat brain lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 50 kDa
Primary incubation: 1 hour
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab115023 被引用在 1 文献中.
- Li F et al. Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing 5-HT3AR and 5-HT3BR Expression in the Rat Brain. Neural Plast 2016:7950781 (2016). PubMed: 27725889