人MIP5 ELISA试剂盒(CCL15)
Human MIP5 ELISA Kit (CCL15)
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(1 Publication)
Human MIP5 ELISA Kit (CCL15) is a Sandwich ELISA for the measurement of Human MIP5 (CCL15) in Human in Biofluids, Cell Culture Media samples.
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MIP5, NCC3, SCYA15, CCL15, C-C motif chemokine 15, Chemokine CC-2, Leukotactin-1, MIP-1 delta, Macrophage inflammatory protein 5, Mrp-2b, NCC-3, Small-inducible cytokine A15, HCC-2, LKN-1, MIP-5
- sELISA
Supplier Data
Sandwich ELISA - Human MIP5 ELISA Kit (CCL15) (AB100598)
Representative Standard Curve using ab100598.
- sELISA
Supplier Data
Sandwich ELISA - Human MIP5 ELISA Kit (CCL15) (AB100598)
Representative Standard Curve using ab100598.
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产品详情
Abcam's MIP5 Human ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human MIP5 in serum, plasma, and cell culture supernatants.
This assay employs an antibody specific for Human MIP5 coated on a 96-well plate. Standards and samples are pipetted into the wells and MIP5 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human MIP5 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of MIP5 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Optimization may be required with urine samples.
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MIP-5 is involved in the chemotactic movement of immune cells a process where cells move in response to chemical stimuli. It is not part of a protein complex but interacts dynamically with cell surface receptors to induce cellular responses. MIP-5 triggers cells to release further signaling molecules increasing the inflammatory response's effectiveness. This chemokine creates a highly coordinated immune response by initiating a signaling cascade that helps maintain immune surveillance and response to pathogens.
Pathways
MIP-5 plays a role in the chemokine signaling pathway where it interacts with specific receptors that lead to cellular migration and activation. It also fits into the cytokine-cytokine receptor interaction pathway influencing a range of cellular responses tied to immune function. MIP-5 shares functional properties with other chemokines like MCP-1 (monocyte chemoattractant protein-1) which similarly attract immune cells and mediate immune responses.
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Recent publications for all applications. Explore the full list and refine your search
Molecular medicine reports 22:5339-5347 PubMed33174007
2020
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