JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB108731

人Anti-Epstein Barr virus IgG ELISA试剂盒(EBV-EBNA)

Human Anti-Epstein Barr virus IgG ELISA Kit (EBV-EBNA)

Be the first to review this product! Submit a review

|

(3 Publications)

Human Anti-Epstein Barr virus IgG ELISA Kit (EBV-EBNA) is an indirect ELISA for the qualitative detection of IgG class antibodies against Epstein Barr virus (EBV-EBNA) in human plasma and serum samples.

- Colorimetric readout - 450 nm - Works on any standard plate reader
- Easy results interpretation
- Cut-off, positive and negative controls included

关键信息

检测方法

Colorimetric

样品类型

Citrate plasma, Heparin Plasma, Serum

反应种属

Human

检测类型

Indirect

检测平台

Microplate

style
left-column

搭配使用产品

Assay Kits

AB108730

Human Anti-Epstein Barr virus IgG ELISA Kit (EBV-VCA)

  • 5
  • 1
Assay Kits

AB108724

Human Anti-Cytomegalovirus IgG ELISA Kit (CMV)

  • 5
  • 2
Assay Kits

AB108732

Human Anti-Epstein Barr virus IgM ELISA Kit (EBV-VCA)

  • 0
  • 0
Assay Kits

AB108725

Human Anti-Cytomegalovirus IgM ELISA Kit (CMV)

  • 5
  • 1
style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
style
left-column

产品详情

<p>Abcam’s anti-Epstein Barr virus (EBV-EBNA) IgG Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the accurate qualitative measurement of IgG class antibodies against Epstein Barr virus nuclear antigen (EBNA) in Human serum and plasma.</p>

<p>A 96-well plate has been precoated with Epstein Barr virus antigens to bind cognate antibodies. Controls or test samples are added to the wells and incubated. Following washing, a horseradish peroxidase (HRP) labelled anti-Human IgG conjugate is added to the wells, which binds to the immobilized Epstein Barr virus-specific antibodies. TMB is then catalyzed by the HRP to produce a blue color product that changes to yellow after adding an acidic stop solution. The density of yellow coloration is directly proportional to the amount of Epstein Barr virus IgG sample captured in plate.</p>

REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.

style
left-column

精确度

[ { "reproducibilityType": "Inter", "sample": "Serum", "replicates": 26, "mean": null, "standardDeviation": null, "coefficientOfVariability": "2.4" }, { "reproducibilityType": "Intra", "sample": "Serum", "replicates": 12, "mean": null, "standardDeviation": null, "coefficientOfVariability": "2" } ]
style
left-column

规格

{ "values": { "1x96Tests": { "sellingSize": "1 x 96 Tests", "publicAssetCode":"ab108731-1x96Tests", "assetComponentDetails": [ { "size":"1 x 1 Unit", "name":"Cover foil", "number":"AB108731-CMP03", "productcode":"" }, { "size":"1 x 100 mL", "name":"IgG Sample Diluent", "number":"AB108731-CMP01", "productcode":"" }, { "size":"1 x 50 mL", "name":"20X Washing Solution", "number":"AB108731-CMP10", "productcode":"" }, { "size":"1 x 15 mL", "name":"Stop Solution", "number":"AB108731-CMP11", "productcode":"" }, { "size":"1 x 15 mL", "name":"TMB Substrate Solution", "number":"AB108731-CMP09", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Strip holder", "number":"AB108731-CMP02", "productcode":"" }, { "size":"1 x 1 Unit", "name":"Epstein Barr virus (IgG) Coated Microplate (12 x 8 wells)", "number":"AB108731-CMP05", "productcode":"" }, { "size":"1 x 20 mL", "name":"Epstein Barr virus anti-IgG HRP Conjugate", "number":"AB108731-CMP04", "productcode":"" }, { "size":"1 x 2 mL", "name":"Epstein-Barr Virus IgG Positive Control", "number":"AB108731-CMP06", "productcode":"" }, { "size":"1 x 2 mL", "name":"Epstein-Barr Virus IgG Negative Control", "number":"AB108731-CMP08", "productcode":"" }, { "size":"1 x 3 mL", "name":"Epstein-Barr Virus IgG Cut-off Control", "number":"AB108731-CMP07", "productcode":"" } ] } } }
style
left-column

性能和储存信息

运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
储存信息
+4°C
style
left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Epstein-Barr virus nuclear antigen (EBNA) IgG is an antibody that targets the Epstein-Barr virus (EBV) which is known for its role in infectious mononucleosis. EBNA proteins are expressed in the lymphocytes infected by EBV primarily B-cells. They play a mechanical role in viral latency and promote cell survival and proliferation. EBNA-1 the most studied of the EBNA family is a protein with a mass of approximately 72 kDa. It is essential for maintaining the episomal form of the EBV genome within the host cell.
Biological function summary

EBNA proteins modulate host cell functions linking them to cell cycle regulation and transcriptional control. They contribute to the transformation of B-cells by interacting with components of the host's cellular machinery. EBNA is not known to form part of a larger protein complex but interacts with host proteins such as the retinoblastoma protein (Rb) and p53 impacting their pathways.

Pathways

EBNA IgG is intricately involved in the EBV latency program and the associated signaling pathways that control cell proliferation and survival. It is part of the pathways that include the NF-kB signaling and apoptotic regulation pathways. EBNA interacts with proteins like LMP1 an EBV-encoded protein that activates NF-kB signaling further integrating itself into the complex network of host-pathogen interactions.

EBNA IgG is significantly associated with the pathogenesis of infectious mononucleosis and certain autoimmune conditions such as multiple sclerosis. In these disorders EBNA interacts with host proteins like Rb leading to cell cycle dysregulation and immune system challenges. The presence of anti-EBNA IgG plays an important role in diagnosing past infection with EBV and assessing the risk for EBV-associated diseases.
style
left-column

产品实验方案

style
left-column

靶点信息

style
left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Nature 640:762-771 PubMed40074901

2025

TGFβ links EBV to multisystem inflammatory syndrome in children.

Applications

Unspecified application

Species

Unspecified reactive species

Carl Christoph Goetzke,Mona Massoud,Stefan Frischbutter,Gabriela Maria Guerra,Marta Ferreira-Gomes,Frederik Heinrich,Anne Sae Lim von Stuckrad,Sebastian Wisniewski,Jan Robin Licha,Marina Bondareva,Lisa Ehlers,Samira Khaldi-Plassart,Etienne Javouhey,Sylvie Pons,Sophie Trouillet-Assant,Yasemin Ozsurekci,Yu Zhang,Maria Cecilia Poli,Valentina Discepolo,Andrea Lo Vecchio,Bengü Sahin,Murielle Verboom,Michael Hallensleben,Anja Isabelle Heuhsen,Camila Astudillo,Yazmin Espinosa,Maria Cecilia Vial Cox,Kerry Dobbs,Ottavia M Delmonte,Gina A Montealegre Sanchez,Mary Magliocco,Karyl Barron,Jeffrey Danielson,Lev Petrov,Nadine Unterwalder,Birgit Sawitzki,Mareen Matz,Katrin Lehmann,Alexander Gratopp,Horst von Bernuth,Lisa-Marie Burkhardt,Niklas Wiese,Lena Peter,Michael Schmueck-Henneresse,Leila Amini,Marcus Maurer,Jobst Fridolin Roehmel,Benjamin E Gewurz,Lael M Yonker,Mario Witkowski,Andrey Kruglov,Marcus Alexander Mall,Helen C Su,Seza Ozen,Andreas Radbruch,Alexandre Belot,Pawel Durek,Tilmann Kallinich,Mir-Farzin Mashreghi

Journal of inflammation (London, England) 21:30 PubMed39135051

2024

Evidence of aberrant anti-epstein-barr virus antibody response, though no viral reactivation, in people with post-stroke fatigue.

Applications

Unspecified application

Species

Unspecified reactive species

Isobel C Mouat,Li Zhu,Alperen Aslan,Barry W McColl,Stuart M Allan,Craig J Smith,Marion S Buckwalter,Laura McCulloch

Nature medicine 25:591-596 PubMed30886409

2019

The repertoire of maternal anti-viral antibodies in human newborns.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Pou,Dieudonné Nkulikiyimfura,Ewa Henckel,Axel Olin,Tadepally Lakshmikanth,Jaromir Mikes,Jun Wang,Yang Chen,Anna Karin Bernhardsson,Anna Gustafsson,Kajsa Bohlin,Petter Brodin
View all publications
style
left-column
style
left-column
websiteProtocolBooklet
en
style
right-column

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com