人Annexin A10 ELISA试剂盒

产品详情

ab222869 Human Annexin A10 ELISA Kit is designed for the quantitative measurement of Annexin A10 in plasma, serum, urine and cell culture samples.

The kit employs a quantitative sandwich enzyme immunoassay technique that measures human Annexin A10 in 4 hours. A polyclonal antibody specific for human Annexin A10 has been pre-coated onto a 96-well microplate with removable strips. Annexin A10 in standards and samples is sandwiched by the immobilized antibody and biotinylated polyclonal antibody specific for Annexin A10, which is recognized by a streptavidin-peroxidase conjugate. All unbound material is washed away and a peroxidase enzyme substrate is added. The color development is stopped and the intensity of the color is measured.

The entire kit may be stored at -20°C for long term storage before reconstitution - Avoid repeated freeze-thaw cycles.

Annexin A10, also known as ANXA10, Annexin-10, or Annexin-14, is a member of the annexin family of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and homologous C-terminal domains containing the calcium-dependent phospholipid-binding sites. Annexin A10 contains deduced 324 amino acids and weighs 37 kDa. It has several distinct features, including rare expression, a codon deletion in conserved repeat 3, and an unusual ablation of the type II calcium-binding sites in tetrad core repeats, indicating a calcium- and membrane-binding-independent function. Annexin A10 has been implicated in cellular functions in endocytosis and exocytosis, anticoagulant activity, cellular differentiation and proliferation, invasion, inhibition of calcium channels, and signal transduction pathways.