10X Annexin V/ANXA5 Binding缓冲液(ab14084)
概述
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产品名称
10X Annexin V/ANXA5 Binding缓冲液
参阅全部 Annexin V/ANXA5 试剂 -
经测试应用
适用于: Flow Cyt, FMmore details -
常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 1006 10X Annexin V Binding Buffer. 1006-100 is the same size as the 100 ml size of ab14084.
The binding buffer contains optimal concentration of calcium which is required for Annexin v/ANXA5 binding to phosphotidylserine (PS) on the cell surface. This 10X reagent should be diluted to 1X with distilled water (ddH2O) before using in the assay.
This buffer can be used in conjunction with our Annexin V/ANXA5 reagents.
性能
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形式
Liquid -
存放说明
Store at +4°C. -
存储溶液
pH: 7.40
Concentrated x10 -
Concentration information loading...
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研究领域
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功能
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. -
疾病相关
Pregnancy loss, recurrent, 3 -
序列相似性
Belongs to the annexin family.
Contains 4 annexin repeats. -
结构域
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
翻译后修饰
S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. - Information by UniProt
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别名
- Anchorin CII
- Annexin 5
- Annexin A5
see all
相关产品
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Related Products
- Annexin V/ANXA5-FITC Apoptosis Detection Reagent (500X) (ab14082)
- Propidium Iodide (ab14083)
- Annexin V-FITC Apoptosis Staining / Detection Kit (ab14085)
- Annexin V-Cy3 Apoptosis Staining / Detection Kit with SYTOX (ab14144)
- Annexin V/ANXA5-Cy5 Apoptosis Staining / Detection Reagent (ab14147)
- Annexin V-Cy5 Apoptosis Staining / Detection Kit (ab14150)
- Annexin V-EGFP Apoptosis Staining / Detection Kit (ab14153)
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab14084于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt |
Use at an assay dependent concentration.
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FM |
Use at an assay dependent concentration.
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说明 |
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Flow Cyt
Use at an assay dependent concentration. |
FM
Use at an assay dependent concentration. |
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (5)
ab14084 被引用在 5 文献中.
- Orniacki C et al. Y-complex nucleoporins independently contribute to nuclear pore assembly and gene regulation in neuronal progenitors. J Cell Sci 136:N/A (2023). PubMed: 37305998
- Nof E et al. Ventilation-induced epithelial injury drives biological onset of lung trauma in vitro and is mitigated with prophylactic anti-inflammatory therapeutics. Bioeng Transl Med 7:e10271 (2022). PubMed: 35600654
- Kochetkova EY et al. Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells. Methods Mol Biol 2445:139-169 (2022). PubMed: 34972991
- Paez-Mayorga J et al. Ponatinib Activates an Inflammatory Response in Endothelial Cells via ERK5 SUMOylation. Front Cardiovasc Med 5:125 (2018). PubMed: 30238007
- Grant R et al. A filtration-based protocol to isolate human Plasma Membrane-derived Vesicles and exosomes from blood plasma. J Immunol Methods 371:143-51 (2011). PubMed: 21741384