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AB166833

Hep G2全细胞裂解物

Hep G2 whole cell lysate

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(3 Publications)

Hep G2 whole cell lysate suitable for WB. View our extensive range of validated lysates from normal and diseased human, mouse and rat tissue.

关键信息

细胞类型

Hep G2

种属

Human

组织

Liver

形式

Liquid

form

疾病

Hepatocellular Carcinoma

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

产品详情

Cell line: HepG2 (Human hepatocellular carcinoma).

Hep G2 whole-cell extract was prepared from cell cultures of the human hepatocellular liver carcinoma HepG2 cell line. These cells are epithelial in morphology and can be induced to exhibit polarization under appropriate culture conditions.

HepG2 cells are most commonly used for studies of hepatocyte function and this HepG2 whole cell lysate is specifically recommended for studies related to:

- human liver diseases, cancers and drug therapies

- HBV etiology

- signaling pathways

- apoptosis

Because of their ability to differentiate into polarized epithelium, these cells are routinely utilized to investigate intracellular protein trafficking, particularly in relation to human liver diseases. HepG2 is the most commonly used cell line in studies pertaining to the regulation of hepatic protein synthesis, particularly the synthesis of acute phase proteins after the onset of a systemic inflammatory response.

In addition, these cells are important for studies related to liver metabolism, liver cancers, liver regeneration, liver cytotoxicity, apoptosis and as a model for hepatitis B virus (HBV) viral etiology.

性能和储存信息

运输条件
Dry Ice
推荐的短期储存条件
-80°C
推荐的长期储存条件
-80°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

细胞培养

生物安全等级

EU: 1 US: 1

贴壁/悬浮

Adherent

性别

Male

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Chemical science 12:10825-10835 PubMed35355937

2021

Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L.

Applications

Unspecified application

Species

Unspecified reactive species

Hoang Anh T Phan,Sam G Giannakoulias,Taylor M Barrett,Chunxiao Liu,E James Petersson

Cell reports. Medicine 2:100218 PubMed33649747

2021

Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters.

Applications

Unspecified application

Species

Unspecified reactive species

Michael S Piepenbrink,Jun-Gyu Park,Fatai S Oladunni,Ashlesha Deshpande,Madhubanti Basu,Sanghita Sarkar,Andreas Loos,Jennifer Woo,Phillip Lovalenti,Derek Sloan,Chengjin Ye,Kevin Chiem,Christopher W Bates,Reuben E Burch,Nathaniel B Erdmann,Paul A Goepfert,Vu L Truong,Mark R Walter,Luis Martinez-Sobrido,James J Kobie

Cell reports. Medicine 2:100218 PubMed33649747

2021

Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters.

Applications

Unspecified application

Species

Unspecified reactive species

Michael S Piepenbrink,Jun-Gyu Park,Fatai S Oladunni,Ashlesha Deshpande,Madhubanti Basu,Sanghita Sarkar,Andreas Loos,Jennifer Woo,Phillip Lovalenti,Derek Sloan,Chengjin Ye,Kevin Chiem,Christopher W Bates,Reuben E Burch,Nathaniel B Erdmann,Paul A Goepfert,Vu L Truong,Mark R Walter,Luis Martinez-Sobrido,James J Kobie
View all publications

Abcam Product Promise

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详情请参阅我们的条款与条件。

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