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AB145857

VGX-1027 (Git-27), TLR4 inhibitior

VGX-1027 (Git-27), TLR4 inhibitor

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MW 205.21 Da, Purity >98%. Immunomodulatory agent. TLR4 inhibitor. TLR4 and TLR 2/6 signaling pathway modulator. Inhibits inflammatory antigen presentation. Inhibits IL1-β, IL-10, IFN-γ and TNF-α secretion. Shows anti-inflammatory effects in vivo. Orally active.
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Chemical Structure - VGX-1027 (Git-27), TLR4 inhibitor (AB145857)
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Chemical Structure - VGX-1027 (Git-27), TLR4 inhibitor (AB145857)

2D chemical structure image of ab145857, VGX-1027 (Git-27), TLR4 inhibitior

关键信息

CAS 号

6501-72-0

纯度

>98%

形式

Solid

form

分子量

205.21 Da

分子式

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>1</sub>NO<sub>3</sub>

PubChem

10798271

属性

Synthetic

溶解度

Soluble in ethanol to 50 mM

Soluble in DMSO to 25 mM

生化试剂名称

4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid

生物学描述

Immunomodulatory agent. TLR4 inhibitor. TLR4 and TLR 2/6 signaling pathway modulator. Inhibits inflammatory antigen presentation. Inhibits IL1-β, IL-10, IFN-γ and TNF-α secretion. Shows anti-inflammatory effects in vivo. Orally active.

经典 SMILES

C1C(ON=C1C2=CC=CC=C2)CC(=O)O

InChi

InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)

InChiKey

MUFJHYRCIHHATF-UHFFFAOYSA-N

IUPAC 名

2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid

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搭配使用产品

Biochemicals

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Biochemicals

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Biochemicals

AB141382

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Biochemicals

AB144858

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Chemical Structure - Ledol, Antifungal agent (AB144858)

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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
储存信息
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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产品实验方案

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