Veratridine，Na+ channel opener (ab120279)
Key features and details
- Na+ channel opener
- CAS Number: 71-62-5
- Soluble in ethanol to 100 mM
- Form / State: Solid
- Source: Liliaceae sp.
概述
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产品名称
Veratridine，Na+ channel opener -
描述
Na+ channel opener -
CAS编号
71-62-5 -
化学结构
性能
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化学名称
3-Veratroylveracevine -
分子量
673.80 -
分子式
C36H51NO11 -
PubChem识别号
6610253 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in ethanol to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc1ccc(cc1OC)C(=O)OC4CC[C@@]7(C)C5CCC6[C@]8(O)C[C@H](O)[C@@]3(O)C(CN2CC(C)CCC2[C@@]3(C)O)[C@]8(O)C[C@@]67O[C@]45O -
来源
Liliaceae sp.
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研究领域
图片
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Chemical Structure - Veratridine, Na+ channel opener (ab120279)2D chemical structure image of ab120279, Veratridine, Na+ channel opener
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab120279 被引用在 6 文献中.
- Wei XP et al. A novel reticular node in the brainstem synchronizes neonatal mouse crying with breathing. Neuron 110:644-657.e6 (2022). PubMed: 34998469
- Mohammed ZA et al. An unbiased and efficient assessment of excitability of sensory neurons for analgesic drug discovery. Pain 161:1100-1108 (2020). PubMed: 31929383
- Sousa SR et al. Discovery and mode of action of a novel analgesic ß-toxin from the African spider Ceratogyrus darlingi. PLoS One 12:e0182848 (2017). PubMed: 28880874
- Mohammed ZA et al. Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons. Sci Rep 7:45221 (2017). PubMed: 28338073
- Henriques ST et al. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7. J Biol Chem 291:17049-65 (2016). PubMed: 27311819
- Zimmermann K et al. Analgesic treatment of ciguatoxin-induced cold allodynia. Pain 154:1999-2006 (2013). PubMed: 23778293