Thioridazine hydrochloride，Dopamine receptor拮抗剂(ab120580)
Key features and details
- Dopamine receptor antagonist
- CAS Number: 130-61-0
- Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Thioridazine hydrochloride，Dopamine receptor拮抗剂 -
描述
Dopamine receptor拮抗剂 -
别名
- THIO
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生物学描述
Dopamine receptor antagonist (Ki values are 16 (D2), 10 (D1), 7.8 (D3), and 31 (D4) nM). Also inhibits CYP2D6 (IC50 = 2.7 μM). Antipsychotic. Displays antituberculosis/ drug-resistant tuberculosis properties.
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CAS编号
130-61-0 -
化学结构
性能
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化学名称
10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride -
分子量
407.03 -
分子式
C21H26N2S2.HCl -
PubChem识别号
66062 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.CN4CCCCC4CCN1c3ccccc3Sc2ccc(SC)cc12 -
来源
Synthetic
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研究领域
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
图片
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Chemical Structure - Thioridazine hydrochloride, Dopamine receptor antagonist (ab120580)2D chemical structure image of ab120580, Thioridazine hydrochloride, Dopamine receptor antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120580 尚未被引用在任何文献中。