Teijin化合物1 hydrochloride,CCR2拮抗剂(ab120823)
Key features and details
- Potent, selective CCR2 antagonist
- CAS Number: 1313730-14-1
- Purity: > 99%
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Teijin化合物1 hydrochloride,CCR2拮抗剂 -
描述
Potent,selective CCR2拮抗剂 -
生物学描述
Potent, selective CCR2 antagonist (Ki = 180 nM). Inhibits cell chemotaxis induced by MCP-1 (EC50 = 24 nM).
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纯度
> 99% -
CAS编号
1313730-14-1 -
化学结构
性能
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化学名称
N-[2-[[(3R)-1-[(4-Chlorophenyl)methyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide hydrochloride -
分子量
476.32 -
分子式
C21H21ClF3N3O2.HCl -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 10 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]3CCN(Cc2ccc(Cl)cc2)C3 -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120823 尚未被引用在任何文献中。