TBB，casein kinase-2 (CK2)抑制剂(ab120988)
Key features and details
- Selective, cell-permeable casein kinase-2 (CK2) inhibitor
- CAS Number: 17374-26-4
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 20 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
TBB，casein kinase-2 (CK2)抑制剂 -
描述
Selective，cell-permeable casein kinase-2 (CK2)抑制剂 -
别名
- NSC 231634
-
生物学描述
Selective, cell-permeable casein kinase-2 (CK2) inhibitor (IC50 = 0.5 μM). Acts in an ATP/GTP competitive manner. Induces apoptosis.
-
纯度
> 98% -
CAS编号
17374-26-4 -
化学结构
性能
-
化学名称
4,5,6,7-Tetrabromo-1H-benzotriazole -
分子量
434.71 -
分子式
C6HBr4N3 -
PubChem识别号
1694 -
存放说明
Store at +4°C. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 20 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
Brc2c1nnnc1c(Br)c(Br)c2Br -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - TBB, casein kinase-2 (CK2) inhibitor (ab120988)2D chemical structure image of ab120988, TBB, casein kinase-2 (CK2) inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120988 被引用在 3 文献中.
- Azad P et al. Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. J Clin Invest 133:N/A (2023). PubMed: 37022795
- Sano K et al. Tyrosine 136 phosphorylation of a-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2. Acta Neuropathol Commun 9:182 (2021). PubMed: 34772466
- González N et al. Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors. PLoS One 11:e0154919 (2016). PubMed: 27144531