Sulindac sulfide，COX-1 and 2抑制剂(ab120650)
Key features and details
- Active metabolite of Sulindac. COX-1 and 2 inhibitor.
- CAS Number: 32004-67-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Sulindac sulfide，COX-1 and 2抑制剂 -
描述
Active metabolite of Sulindac. COX-1 and 2抑制剂. -
生物学描述
Cell-permeable, active metabolite of Sulindac. Inhibits Ras-induced malignant transformation and Ras/Raf-dependent transactivation. COX-1 and 2 inhibitor (Ki values are 1.02 and 10.43 μM, respectively). Additionally, inhibits γ-secretase. Apoptosis inducer.
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纯度
> 98% -
CAS编号
32004-67-4 -
化学结构
性能
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化学名称
(Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic acid -
分子量
340.41 -
分子式
C20H17FO2S -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
图片
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Chemical Structure - Sulindac sulfide, COX-1 and 2 inhibitor (ab120650)2D chemical structure image of ab120650, Sulindac sulfide, COX-1 and 2 inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
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