Strychnine hydrochloride，Glycine拮抗剂(ab120416)
Key features and details
- Glycine antagonist
- CAS Number: 1421-86-9
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Strychnos sp.
概述
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产品名称
Strychnine hydrochloride，Glycine拮抗剂 -
描述
Glycine拮抗剂 -
生物学描述
Competitive glycine receptor antagonist. Convulsant. Also antagonist at α7 receptors and α4β2 nicotinic receptors.
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CAS编号
1421-86-9 -
化学结构
性能
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化学名称
Strychnidin-10-one hydrochloride -
分子量
370.87 -
分子式
C21H22N2O2.HCl -
PubChem识别号
16219987 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.O=C2C[C@@H]7OCC=C6CN4CC[C@@]53c1ccccc1N2C3[C@H]7[C@H]6C[C@H]45 -
来源
Strychnos sp.
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研究领域
图片
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Chemical Structure - Strychnine hydrochloride, Glycine antagonist (ab120416)2D chemical structure image of ab120416, Strychnine hydrochloride, Glycine antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (30)
ab120416 被引用在 30 文献中.
- Tasnim A et al. The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders. Nat Neurosci 27:484-496 (2024). PubMed: 38233682
- Chou MY et al. Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice. Commun Biol 6:267 (2023). PubMed: 36918719
- Chen HC et al. Differentiation, Transcriptomic Profiling, and Calcium Imaging of Human Hypothalamic Neurons. Curr Protoc 3:e786 (2023). PubMed: 37272700
- Martín-de-Saavedra MD et al. Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2. Neuron 110:627-643.e9 (2022). PubMed: 34921780
- Huang DF et al. Neuronal splicing regulator RBFOX3 mediates seizures via regulating Vamp1 expression preferentially in NPY-expressing GABAergic neurons. Proc Natl Acad Sci U S A 119:e2203632119 (2022). PubMed: 35951651