SNAP，NO donor (ab120014)
Key features and details
- NO donor
- CAS Number: 67776-06-1
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
SNAP，NO donor -
描述
NO donor -
生物学描述
NO donor. Vasodilator in vitro and in vivo, that does not induce pharmacological tolerance.
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CAS编号
67776-06-1 -
化学结构
性能
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化学名称
S-Nitroso-N-acetyl-DL-penicillamin -
分子量
220.24 -
分子式
C7H12N2O4S -
PubChem识别号
5231 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(SN=O)C(NC(=O)C)C(=O)O -
来源
Synthetic
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研究领域
- Biochemicals
- Pharmacology
- Signaling
- Signal transduction
- Nitric oxide & oxidative stress
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Alzheimer's Disease
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Diabetes
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Hypertension
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
- Biochemicals
- Research Area
- Obesity
- Signaling
- Signal transduction
- Nitric oxide signaling
- Donors / precursors
- Donors
图片
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Chemical Structure - SNAP, NO donor (ab120014)2D chemical structure image of ab120014, SNAP, NO donor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (7)
ab120014 被引用在 7 文献中.
- Oliver AA et al. Analysis of vascular inflammation against bioresorbable Zn-Ag based alloys. ACS Appl Bio Mater 3:6779-6789 (2020). PubMed: 33644704
- Zhou MH et al. Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation. J Biol Chem 290:30616-23 (2015). PubMed: 26507659
- Elies J et al. Inhibition of the cardiac na+ channel nav1.5 by carbon monoxide. J Biol Chem 289:16421-9 (2014). PubMed: 24719320
- Sieber AR et al. Non-Hebbian long-term potentiation of inhibitory synapses in the thalamus. J Neurosci 33:15675-85 (2013). PubMed: 24089475
- Jin XG et al. Nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons. J Biol Chem 286:33190-202 (2011). PubMed: 21813646
- Fenselau H et al. Heterosynaptic long-term potentiation at GABAergic synapses of spinal lamina I neurons. J Neurosci 31:17383-91 (2011). PubMed: 22131400
- Bright DP & Brickley SG Acting locally but sensing globally: impact of GABAergic synaptic plasticity on phasic and tonic inhibition in the thalamus. J Physiol 586:5091-9 (2008). PubMed: 18772202