SEW 2871，S1P1激动剂(ab120983)
Key features and details
- Potent, selective S1P1 agonist
- CAS Number: 256414-75-2
- Purity: > 98%
- Soluble in DMSO to 20 mM and in ethanol to 20 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
SEW 2871，S1P1激动剂 -
描述
Potent，selective S1P1激动剂 -
生物学描述
Potent, selective sphingosine-1-phosphate (S1P1) agonist (EC50 = 13 nM). Does not activate S1P2, S1P3, S1P4 or S1P5 receptors. Cell-permeable and active in vivo.
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纯度
> 98% -
CAS编号
256414-75-2 -
化学结构
性能
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化学名称
5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole -
分子量
440.36 -
分子式
C20H10F6N2OS -
PubChem识别号
4077460 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 20 mM and in ethanol to 20 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
FC(F)(F)c2sc(cc2c1ccccc1)c3nc(no3)c4cccc(c4)C(F)(F)F -
来源
Synthetic
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研究领域
图片
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Chemical Structure - SEW 2871, S1P1 agonist (ab120983)2D chemical structure image of ab120983, SEW 2871, S1P1 agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120983 被引用在 1 文献中.
- Cao J et al. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun 8:2210 (2017). PubMed: 29263363