SB 399885 hydrochloride，5-HT6拮抗剂(ab120332)
Key features and details
- Potent, selective 5-HT6 antagonist
- CAS Number: 402713-80-8
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
SB 399885 hydrochloride，5-HT6拮抗剂 -
描述
Potent，selective 5-HT6拮抗剂 -
生物学描述
Potent, selective competitive 5-HT6 antagonist (pKi values are 8.81 and 9.02 for rat and human native receptors, respectively). Orally active, cognitive enhancer in vivo. Displays >200-fold selectivity over 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT4, 5-HT7, α1B, D2, D3, D4 receptors, ion channels and a range of enzymes.
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CAS编号
402713-80-8 -
化学结构
性能
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化学名称
N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide hydrochloride -
分子量
482.81 -
分子式
C18H21Cl2N3O4S.HCl -
PubChem识别号
10277652 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Clc3cc(NS(=O)(=O)c1cc(c(cc1)OC)N2CCNCC2)c(OC)c(Cl)c3 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - SB 399885 hydrochloride, 5-HT6 antagonist (ab120332)2D chemical structure image of ab120332, SB 399885 hydrochloride, 5-HT6 antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120332 尚未被引用在任何文献中。