(S)-(-)-Raclopride，D2 receptor拮抗剂(ab120563)
Key features and details
- D2 receptor antagonist
- CAS Number: 84225-95-6
- Purity: > 97%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(S)-(-)-Raclopride，D2 receptor拮抗剂 -
描述
D2 receptor拮抗剂 -
生物学描述
High affinity (Kd = 1.2 nM) and high selectivity for D2 receptors in vitro and in vivo (IC50 = 32 nM). Centrally active following systemic administration.
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纯度
> 97% -
CAS编号
84225-95-6 -
化学结构
性能
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化学名称
3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide -
分子量
347.24 -
分子式
C15H20Cl2N2O3 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
图片
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Chemical Structure - (S)-(-)-Raclopride, D2 receptor antagonist (ab120563)2D chemical structure image of ab120563, (S)-(-)-Raclopride, D2receptor antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120563 被引用在 1 文献中.
- Nagai Y et al. Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience. Cell Rep 42:112149 (2023). PubMed: 36821440