RuBi-GABA，caged-GABA化合物

关键信息

CAS 号

1028141-88-9

形式

Solid

form

分子量

922.8 Da

分子式

C₄₂H₃₉F₆N₅O₂P₂Ru

PubChem

129316180

属性

Synthetic

溶解度

Soluble in DMSO to 25 mM

For water solubility, please refer to Guideline for Use Information Sheet

生化试剂名称

RuBi-GABA

生物学描述

Novel caged-GABA compound that uses a ruthenium complex as photosensor. Can be excited with visible wavelengths, providing greater tissue penetration, less photo-toxicity, and faster photorelease kinetics than other UV light-sensitive caged compounds. Can be used for GABA receptor mapping, and optical silencing of neuronal firing.

经典 SMILES

C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3.C1=CC=NC(=C1)C2=CC=CC=N2.C1=CC=NC(=C1)C2=CC=CC=N2.C(CC(=O)[O-])CN.F[P-](F)(F)(F)(F)F.[Ru+2]

InChi

InChI=1S/C18H15P.2C10H8N2.C4H9NO2.F6P.Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;5-3-1-2-4(6)7;1-7(2,3,4,5)6;/h1-15H;2*1-8H;1-3,5H2,(H,6,7);;/q;;;;-1;+2/p-1

InChiKey

SWFWLLYVSYURHZ-UHFFFAOYSA-M

IUPAC 名

4-aminobutanoate;2-pyridin-2-ylpyridine;ruthenium(2+);triphenylphosphane;hexafluorophosphate