(R,S)-CHPG sodium salt，mGlu5激动剂; water soluble (ab120221)
Key features and details
- mGlu5 agonist; water soluble
- CAS Number: 1303993-73-8
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(R,S)-CHPG sodium salt，mGlu5激动剂; water soluble -
描述
mGlu5激动剂; water soluble -
生物学描述
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纯度
> 99% -
CAS编号
1303993-73-8 -
化学结构
性能
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化学名称
(R,S)-2-Amino-2-(2-chloro-5-hydroxyphenyl)acetic acid sodium salt -
分子量
223.59 -
分子式
C8H7ClNNaO3 -
PubChem识别号
52974246 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NC(c1cc(O)ccc1Cl)C(=O)O[Na] -
来源
Synthetic
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研究领域
相关产品
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图片
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Chemical Structure - (R,S)-CHPG sodium salt, mGlu5 agonist; water soluble (ab120221)2D chemical structure image of ab120221, (R,S)-CHPG sodium salt, mGlu5 agonist; water soluble
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (4)
ab120221 被引用在 4 文献中.
- Hu C et al. Different Aberrant Changes of mGluR5 and Its Downstream Signaling Pathways in the Scrapie-Infected Cell Line and the Brains of Scrapie-Infected Experimental Rodents. Front Cell Dev Biol 10:844378 (2022). PubMed: 35646890
- Suryavanshi PS et al. Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus. Mol Pharmacol 90:96-105 (2016). PubMed: 27231330
- Besheer J et al. Stress Hormone Exposure Reduces mGluR5 Expression in the Nucleus Accumbens: Functional Implications for Interoceptive Sensitivity to Alcohol. Neuropsychopharmacology : (2014). PubMed: 24713611
- Kammermeier PJ The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency. BMC Pharmacol 12:6 (2012). PubMed: 22642439