(R,S)-Baclofen，GABAB激动剂(ab120149)
Key features and details
- GABAB agonist
- CAS Number: 1134-47-0
- Soluble in 1 eq. NaOH to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(R,S)-Baclofen，GABAB激动剂 -
描述
GABAB激动剂 -
生物学描述
Selective GABAB receptor agonist. Antispasmodic.
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CAS编号
1134-47-0 -
化学结构
性能
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化学名称
(R,S)-4-Amino-3-(4-chlorophenyl)butanoic acid -
分子量
213.66 -
分子式
C10H12ClNO2 -
PubChem识别号
2284 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in 1 eq. NaOH to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Clc1ccc(cc1)C(CN)CC(=O)O -
来源
Synthetic
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研究领域
图片
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Chemical Structure - (R,S)-Baclofen, GABAB agonist (ab120149)2D chemical structure image of ab120149, (R,S)-Baclofen, GABAB agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120149 被引用在 3 文献中.
- Guo C et al. Purkinje cell outputs selectively inhibit a subset of unipolar brush cells in the input layer of the cerebellar cortex. Elife 10:N/A (2021). PubMed: 34369877
- Copits BA et al. A photoswitchable GPCR-based opsin for presynaptic inhibition. Neuron 109:1791-1809.e11 (2021). PubMed: 33979635
- Sousa VC et al. Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of ?9-tetrahydrocannabinol on spatial memory. Neuropsychopharmacology 36:472-87 (2011). PubMed: 20927050