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AB120982

RS 102221 hydrochloride，5-HT2C receptor拮抗剂

RS 102221 hydrochloride, 5-HT2C receptor antagonist

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MW 649.08 g/mol, Purity >98%. Selective, high affinity 5-HT2C receptor antagonist (pKi = 8.4). Displays approximately 100-fold selectivity over the 5-HT2A and 5-HT2B subtypes and > 100-fold selectivity over other 5-HT receptors, α- and β-adrenergic and muscarinic ACh receptors.
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Chemical Structure - RS 102221 hydrochloride, 5-HT2C receptor antagonist (AB120982)
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Chemical Structure - RS 102221 hydrochloride, 5-HT2C receptor antagonist (AB120982)

2D chemical structure image of ab120982, RS 102221 hydrochloride, 5-HT2C receptor antagonist

关键信息

CAS 号

187397-18-8

纯度

>98%

形式

Solid

form

分子量

649.08 g/mol

属性

Synthetic

溶解度

Soluble in DMSO to 100 mM

生物学描述

Selective, high affinity 5-HT2C receptor antagonist (pKi = 8.4). Displays approximately 100-fold selectivity over the 5-HT2A and 5-HT2B subtypes and > 100-fold selectivity over other 5-HT receptors, α- and β-adrenergic and muscarinic ACh receptors.

经典 SMILES

CL.FC(F)(F)C1CCC(CC1)S(=O)(=O)NC2CC(C(OC)CC2OC)C(=O)CCCCN4CCC3(NC(=O)NC3=O)CC4

InChi

InChI=1S/C27H31F3N4O7S.ClH/c1-40-22-16-23(41-2)20(33-42(38,39)18-8-6-17(7-9-18)27(28,29)30)15-19(22)21(35)5-3-4-12-34-13-10-26(11-14-34)24(36)31-25(37)32-26;/h6-9,15-16,33H,3-5,10-14H2,1-2H3,(H2,31,32,36,37);1H

InChiKey

SZJZEJZLRDIHPB-UHFFFAOYSA-N

IUPAC 名

N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-<br />oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamide hydrochloride

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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
Ambient
推荐的长期储存条件
Ambient
储存信息
Store under desiccating conditions
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产品实验方案

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搭配使用产品

Biochemicals

AB120420

Buspirone hydrochloride, 5-HT1A agonist

Chemical Structure - Buspirone hydrochloride, 5-HT1A agonist (AB120420)

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Biochemicals

AB120550

WAY-100635 maleate, 5-HT1A receptor antagonist

Chemical Structure - WAY-100635 maleate, 5-HT1A receptor antagonist (AB120550)

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Biochemicals

AB120133

Citalopram, 5-HT reuptake inhibitor

Chemical Structure - Citalopram, 5-HT reuptake inhibitor (AB120133)

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Biochemicals

AB143952

1,2-Dimyristoyl-sn-glycero-3-phosphorylglycerol sodium salt (DMPG), Phosphatidylglycerol

Chemical Structure - 1,2-Dimyristoyl-sn-glycero-3-phosphorylglycerol sodium salt (DMPG), Phosphatidylglycerol (AB143952)

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