Rhodadyn™ C10,cell-permeable dynamin I抑制剂(ab120795)
Key features and details
- Highly potent cell-permeable dynamin I inhibitor
- CAS Number: 1367579-04-1
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Rhodadyn™ C10,cell-permeable dynamin I抑制剂 -
描述
Highly potent cell-permeable dynamin I抑制剂 -
生物学描述
Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC50 = 7.0 μM).
Rhodadyn™ B10 negative control also available (ab120796).
Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012). -
纯度
> 98% -
常规说明
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd. -
CAS编号
1367579-04-1 -
化学结构
性能
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化学名称
(5Z)-5-[4-[3-(Dimethylamino)propoxy]benzylidene]-3-ethyl-2-thioxo-1,3-thiazolidin-4-one -
分子量
350.49 -
分子式
C17H22N2O2S2 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM -
处理
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120795 尚未被引用在任何文献中。