(R)-(+)-8-Hydroxy-DPAT hydrobromide (8-Hydroxy DPAT)，5-HT1A receptor激动剂(ab120507)
Key features and details
- Selective full 5-HT1A receptor agonist
- CAS Number: 78095-19-9
- Soluble in water to 20 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(R)-(+)-8-Hydroxy-DPAT hydrobromide (8-Hydroxy DPAT)，5-HT1A receptor激动剂 -
描述
Selective full 5-HT1A receptor激动剂 -
别名
- 8-Hydroxy DPAT
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生物学描述
Selective full 5-HT1A receptor agonist. More active enantiomer of 8-OH-DPAT. Displays greater efficacy at 5-HT1A. Also displays moderate affinity at 5-HT7. Inhibits amphetamine induced dopamine release.
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CAS编号
78095-19-9 -
化学结构
性能
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化学名称
(2R)-(+)-8-Hydroxy-2-(di-n-propylamino)tetralin hydrobromide -
分子量
328.29 -
分子式
C16H25NO.HBr -
PubChem识别号
11957570 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 20 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCN(CCC)[C@@H]1CCC2=C(C1)C(=CC=C2)O.Br -
来源
Synthetic
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研究领域
相关产品
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Related Products
图片
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Chemical Structure - (R)-(+)-8-Hydroxy-DPAT hydrobromide (8-Hydroxy DPAT), 5-HT1A receptor agonist (ab120507)2D chemical structure image of ab120507, (R)-(+)-8-Hydroxy-DPAT hydrobromide (8-Hydroxy DPAT), 5-HT1A receptor agonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120507 被引用在 1 文献中.
- Qian YW et al. HIV-1 gp120 Glycoprotein Interacting with Dendritic Cell-specific Intercellular Adhesion Molecule 3-grabbing Non-integrin (DC-SIGN) Down-Regulates Tight Junction Proteins to Disrupt the Blood Retinal Barrier and Increase Its Permeability. J Biol Chem 291:22977-22987 (2016). PubMed: 27605665