Quetiapine hemifumarate,D2 and 5-HT2 antagonis (ab120737)
Key features and details
- D2 and 5-HT2 antagonist. Antipsychotic.
- CAS Number: 111974-72-2
- Purity: > 99%
- Soluble in DMSO to 25 mM (with sonication)
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Quetiapine hemifumarate,D2 and 5-HT2 antagonis -
描述
D2 and 5-HT2拮抗剂. Antipsychotic. -
生物学描述
D2 and 5-HT2 antagonist. IC50 values (nM) are 329 (D2), 1243 (D1), 148 (5-HT2), 720 (5-HT1A), 90 (α1), 270 (α2), muscarinic (>10,000) and benzodiazepine (>10,000). Antipsychotic. Centrally active following oral administration.
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纯度
> 99% -
CAS编号
111974-72-2 -
化学结构
性能
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化学名称
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate -
分子量
441.54 -
分子式
C21H25N3O2S.0.5C4H4O4 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM (with sonication) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
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