Prostaglandin J2，PGD2 analog (ab120913)
Key features and details
- Endogenous product of inflammation; PGD2 analog
- CAS Number: 60203-57-8
- Purity: > 95%
- Supplied in methyl acetate (5 mg/ml)
- Form / State: Liquid
- Source: Synthetic
概述
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产品名称
Prostaglandin J2，PGD2 analog -
描述
Endogenous product of inflammation; PGD2 analog -
别名
- PGJ2
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纯度
> 95% -
CAS编号
60203-57-8 -
化学结构
性能
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化学名称
(5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9,13-trien-1-oic acid -
分子量
334.45 -
分子式
C20H30O4 -
存放说明
Store at -80°C. -
溶解度概述
Supplied in methyl acetate (5 mg/ml) -
处理
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCCCCC(O)/C=C/[C@@H]1C(C/C=CCCCC(=O)O)C=CC1=O -
来源
Synthetic
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研究领域
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab120913于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Functional Studies |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
Functional Studies
Use at an assay dependent concentration. |
图片
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Chemical Structure - Prostaglandin J2, PGD2 analog (ab120913)2D chemical structure image of ab120913, Prostaglandin J2, PGD2 analog
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Immunocytochemistry/ Immunofluorescence - Prostaglandin J2, PGD2 analog (ab120913)ab80579 staining tau in SKNSH cells treated with prostaglandin J2 (ab120913), by ICC/IF. Expression of tau expression is restringed to the perinuclear zone with increased concentration of prostaglandin J2, as described in literature.
The cells were incubated at 37°C for 6 hours in media containing different concentrations of ab120913 (prostaglandin J2) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab80579 (10 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei (blue) were counterstained with DAPI and membrane is was stained using WGA (red).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab120913 尚未被引用在任何文献中。