(±)-Thalidomide，Immunomodulator and anticancer agent (ab120032)
Key features and details
- Immunomodulator and anticancer agent
- CAS Number: 50-35-1
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
(±)-Thalidomide，Immunomodulator and anticancer agent -
描述
Immunomodulator and anticancer agent -
生物学描述
Immunomodulator. Antiproliferative, antiangiogenic and pro-apoptotic.
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CAS编号
50-35-1 -
化学结构
性能
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化学名称
N-(2,6-Dioxo-3-piperidinyl)phthalimide -
分子量
258.23 -
分子式
C13H10N2O4 -
PubChem识别号
5426 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C1NC(=O)CCC1N3C(=O)c2ccccc2C3=O -
来源
Synthetic
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研究领域
图片
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Chemical Structure - (±)-Thalidomide, Immunomodulator and anticancer agent (ab120032)2D chemical structure image of ab120032, Thalidomide, Immunomodulator and anticancer agent
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120032 被引用在 3 文献中.
- Bouguenina H et al. iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells. iScience 26:107059 (2023). PubMed: 37360684
- Rosa TLSA et al. The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum. Front Med (Lausanne) 9:899998 (2022). PubMed: 35733868
- Quayle LA et al. Anti-angiogenic drugs: direct anti-cancer agents with mitochondrial mechanisms of action. Oncotarget 8:88670-88688 (2017). PubMed: 29179466