Pifithrin-alpha-HBr，p53抑制剂(ab120478)
Key features and details
- p53 Inhibitor
- CAS Number: 63208-82-2
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Pifithrin-alpha-HBr，p53抑制剂 -
描述
p53抑制剂 -
常规说明
Pifithrin-?-HBr is light senstive and it is recommended that the compound is protected from light.
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CAS编号
63208-82-2 -
化学结构
性能
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化学名称
1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide -
分子量
367.30 -
分子式
C16H18N2OS.HBr -
PubChem识别号
9929138 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Br.Cc1ccc(cc1)C(=O)CN2C=3CCCCC=3SC2=N -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Pifithrin-alpha-HBr, p53 Inhibitor (ab120478)2D chemical structure image of ab120478, Pifithrin-alpha-HBr, p53 Inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (5)
ab120478 被引用在 5 文献中.
- Nakai K et al. Streptozotocin induces renal proximal tubular injury through p53 signaling activation. Sci Rep 13:8705 (2023). PubMed: 37248327
- Jia J et al. Transcriptional factor FoxM1-activated microRNA-335-3p maintains the self-renewal of neural stem cells by inhibiting p53 signaling pathway via Fmr1. Stem Cell Res Ther 12:169 (2021). PubMed: 33691791
- Zhan H et al. Downregulation of miR-128 Ameliorates Ang II-Induced Cardiac Remodeling via SIRT1/PIK3R1 Multiple Targets. Oxid Med Cell Longev 2021:8889195 (2021). PubMed: 34646427
- Uehara M et al. Pharmacological inhibition of ataxia-telangiectasia mutated exacerbates acute kidney injury by activating p53 signaling in mice. Sci Rep 10:4441 (2020). PubMed: 32157166
- Li S et al. Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway. Cancer Cell Int 17:98 (2017). PubMed: 29093644