PF 670462，casein kinase 1epsilon (CK1epsilon) and CK1delta抑制剂(ab120985)
Key features and details
- Potent, selective casein kinase 1ε (CK1ε) and CK1δ inhibitor
- CAS Number: 950912-80-8
- Purity: > 99%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
PF 670462，casein kinase 1epsilon (CK1epsilon) and CK1delta抑制剂 -
描述
Potent，selective casein kinase 1ε (CK1ε) and CK1δ抑制剂 -
生物学描述
Potent, selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM for CK1ε and CK1δ, respectively). Shows >300-fold selectivity over CK2 and selectivity over more than 40 other kinases. Alters circadian rhythms in vivo.
Also available in simple stock solutions (ab146728) - add 1 ml of water to get an exact, ready-to-use concentration. -
纯度
> 99% -
CAS编号
950912-80-8 -
化学结构
性能
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化学名称
4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride -
分子量
410.32 -
分子式
C19H20FN5.2HCl -
PubChem识别号
51049607 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.Nc1nccc(n1)c3c(ncn3C2CCCCC2)c4ccc(F)cc4 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - PF 670462, casein kinase 1epsilon (CK1epsilon) and CK1delta inhibitor (ab120985)2D chemical structure image of ab120985, PF 670462, casein kinase 1epsilon (CK1epsilon) and CK1delta inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120985 尚未被引用在任何文献中。