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AB141265

Pargyline hydrochloride，Monoamine oxidase (MAO)抑制剂

Pargyline hydrochloride, Monoamine oxidase (MAO) inhibitor

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(2 Publications)

MW 195.69 Da, Purity >99%. Monoamine oxidase (MAO) inhibitor (IC50 = 0.9 μM). Orally active in vivo.
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Chemical Structure - Pargyline hydrochloride, Monoamine oxidase (MAO) inhibitor (AB141265)
  • Chemical Structure

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Chemical Structure - Pargyline hydrochloride, Monoamine oxidase (MAO) inhibitor (AB141265)

2D chemical structure image of ab141265, Pargyline hydrochloride, Monoamine oxidase (MAO) inhibitor

关键信息

CAS 号

306-07-0

纯度

>99%

形式

Solid

form

分子量

195.69 Da

分子式

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>4</sub>ClN

PubChem

9373

属性

Synthetic

溶解度

Soluble in water to 100 mM

Soluble in ethanol to 100 mM

生化试剂名称

Pargyline hydrochloride

生物学描述

Monoamine oxidase (MAO) inhibitor (IC50 = 0.9 μM). Orally active in vivo.

经典 SMILES

CN(CC#C)CC1=CC=CC=C1.Cl

InChi

InChI=1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChiKey

BCXCABRDBBWWGY-UHFFFAOYSA-N

IUPAC 名

N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride

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搭配使用产品

Biochemicals

AB120609

Reserpine, Irreversible vesicular monoamine transporter antagonist

Chemical Structure - Reserpine, Irreversible vesicular monoamine transporter antagonist (AB120609)

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Biochemicals

AB120867

FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate

Chemical Structure - FFN202 (Mini 202), Fluorescent VMAT1 and VMAT2 substrate (AB120867)

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Biochemicals

AB141501

Digitonin, detergent for solubilizing receptors and cellular membranes

Chemical Structure - Digitonin, detergent for solubilizing receptors and cellular membranes (AB141501)

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Biochemicals

AB120866

FFN102 (Mini 102), Fluorescent DAT and VMAT2 substrate

Functional Studies (Act) - FFN102 (Mini 102), Fluorescent DAT and VMAT2 substrate (AB120866)

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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
储存信息
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

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产品实验方案

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Science advances 10:eadp6301 PubMed39565858

2024

Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA-induced dyskinetic behaviors.

Applications

Unspecified application

Species

Unspecified reactive species

Beatriz E Nielsen,Christopher P Ford

Frontiers in bioengineering and biotechnology 12:1335474 PubMed38328444

2024

Continuous long-range measurement of tonic dopamine with advanced FSCV for pharmacodynamic analysis of levodopa-induced dyskinesia in Parkinson's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Jeongrak Park,Seongtak Kang,Yaebin Lee,Ji-Woong Choi,Yong-Seok Oh
View all publications
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