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AB141724

P32/98，dipeptidyl peptidase IV (DPP4)抑制剂

P32/98, dipeptidyl peptidase IV (DPP4) inhibitor

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MW 318.39 Da, Purity >98%. Potent, selective dipeptidyl peptidase IV (DPP4) inhibitor (IC50 = 131 nM). Orally active. Enhances glucose tolerance through increased insulin secretion. Active in vivo.
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Chemical Structure - P32/98, dipeptidyl peptidase IV (DPP4) inhibitor (AB141724)
  • Chemical Structure

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Chemical Structure - P32/98, dipeptidyl peptidase IV (DPP4) inhibitor (AB141724)

2D chemical structure image of ab141724, P32/98, dipeptidyl peptidase IV (DPP4) inhibitor

关键信息

CAS 号

251572-86-8

纯度

>98%

分子量

318.39 Da

分子式

C<sub>1</sub><sub>3</sub>H<sub>2</sub><sub>2</sub>N<sub>2</sub>O<sub>5</sub>S

PubChem

6918464

属性

Synthetic

溶解度

Soluble in water to 75 mM

Soluble in DMSO to 75 mM

生化试剂名称

Thiazolidine,3-[(2S,3S)-2-aMino-3-Methyl-1-oxopentyl]-, (2E)-2-butenedioate (2

生物学描述

Potent, selective dipeptidyl peptidase IV (DPP4) inhibitor (IC50 = 131 nM). Orally active. Enhances glucose tolerance through increased insulin secretion. Active in vivo.

经典 SMILES

CCC(C)C(C(=O)N1CCSC1)N.C(=CC(=O)O)C(=O)O

同分异构的 SMILES

CC[C@H](C)[C@@H](C(=O)N1CCSC1)N.C(=C/C(=O)O)\C(=O)O

InChi

InChI=1S/C9H18N2OS.C4H4O4/c1-3-7(2)8(10)9(12)11-4-5-13-6-11;5-3(6)1-2-4(7)8/h7-8H,3-6,10H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t7-,8-;/m0./s1

InChiKey

ZSOPWZQRZHWYFY-NUXPJIRBSA-N

IUPAC 名

(2S,3S)-2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)pentan-1-one;(E)-but-2-enedioic acid

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搭配使用产品

Biochemicals

AB145599

Diprotin A, Dipeptidyl peptidase IV inhibitor

Chemical Structure - Diprotin A, Dipeptidyl peptidase IV inhibitor (AB145599)

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Biochemicals

AB142171

NVP DPP 728, DPP-IV inhibitor

Chemical Structure - NVP DPP 728, DPP-IV inhibitor (AB142171)

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Biochemicals

AB235551

Teneligliptin, DPP-4 inhibitor

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Biochemicals

AB144783

N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neurotoxin

Chemical Structure - N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neurotoxin (AB144783)

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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
储存信息
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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产品实验方案

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