Oxytocin，Reproductive hormone (ab120186)
Key features and details
- Reproductive hormone
- CAS Number: 50-56-6
- Soluble in water
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
Oxytocin，Reproductive hormone -
描述
Reproductive hormone -
生物学描述
Involved in many aspects of mammalian reproduction as well as other physiological processes such as bond pairing and cardiovascular homeostasis.
-
CAS编号
50-56-6 -
化学结构
性能
-
分子量
1007.19 -
分子式
C43H66N12O12S2 -
序列
CYIQNCPLG (Modifications: C-terminal amide; Disulfide bonds: 1-6) -
PubChem识别号
439302 -
存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
来源
Synthetic
-
研究领域
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab120186于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| Functional Studies |
Use at an assay dependent concentration.
|
| 说明 |
|---|
|
Functional Studies
Use at an assay dependent concentration. |
图片
-
Chemical Structure - Oxytocin, Reproductive hormone (ab120186)2D chemical structure image of ab120186, Oxytocin, Reproductive hormone
-
Functional Studies - Oxytocin, Reproductive hormone (ab120186)ab87312 staining oxytocin receptor in MCF7 cells treated with oxytocin (ab120186), by ICC/IF. Increase of cytoplasmatic oxytocin receptor localization and correspondent decrease in nuclear oxytocin receptor correlates with increased concentration of oxytocin, as described in literature.
The cells were incubated at 37°C for 15 minutes in media containing different concentrations of ab120186 (oxytocin) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab87312 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 donkey anti-goat polyclonal antibody (ab96931) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120186 被引用在 3 文献中.
- Rana M et al. Highly Specific Detection of Oxytocin in Saliva. Int J Mol Sci 24:N/A (2023). PubMed: 36902261
- Yuan J et al. The effects of oxytocin to rectify metabolic dysfunction in obese mice are associated with increased thermogenesis. Mol Cell Endocrinol 514:110903 (2020). PubMed: 32531419
- Yamagishi A et al. Oxytocin administration modulates rats' helping behavior depending on social context. Neurosci Res N/A:N/A (2019). PubMed: 30953682