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AB142171

NVP DPP 728，DPP-IV抑制剂

NVP DPP 728, DPP-IV inhibitor

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(1 Publication)

MW 371.3 Da, Purity >98%. Potent, selective, reversible dipeptidyl peptidase-IV (DPP-IV) inhibitor (Ki = 11 nM). Antidiabetic agent in vivo. Orally active.
1 Images
Chemical Structure - NVP DPP 728, DPP-IV inhibitor (AB142171)
  • Chemical Structure

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Chemical Structure - NVP DPP 728, DPP-IV inhibitor (AB142171)

2D chemical structure image of ab142171, NVP DPP 728, DPP-IV inhibitor

关键信息

CAS 号

207556-62-5

纯度

>98%

形式

Solid

form

分子量

371.3 Da

分子式

C<sub>1</sub><sub>5</sub>H<sub>2</sub><sub>0</sub>Cl<sub>2</sub>N<sub>6</sub>O

PubChem

9799555

属性

Synthetic

溶解度

Soluble in water to 100 mM

Soluble in DMSO to 100 mM

生化试剂名称

Nvp dpp 728 dihydrochloride

生物学描述

Potent, selective, reversible dipeptidyl peptidase-IV (DPP-IV) inhibitor (Ki = 11 nM). Antidiabetic agent in vivo. Orally active.

经典 SMILES

C1CC(N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N.Cl.Cl

同分异构的 SMILES

C1C[C@H](N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N.Cl.Cl

InChi

InChI=1S/C15H18N6O.2ClH/c16-8-12-3-4-14(20-10-12)19-6-5-18-11-15(22)21-7-1-2-13(21)9-17;;/h3-4,10,13,18H,1-2,5-7,11H2,(H,19,20);2*1H/t13-;;/m0../s1

InChiKey

VNACOBVZDCLAEV-GXKRWWSZSA-N

IUPAC 名

6-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]ethylamino]pyridine-3-carbonitrile;dihydrochloride

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搭配使用产品

Biochemicals

AB145599

Diprotin A, Dipeptidyl peptidase IV inhibitor

Chemical Structure - Diprotin A, Dipeptidyl peptidase IV inhibitor (AB145599)

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Biochemicals

AB141724

P32/98, dipeptidyl peptidase IV (DPP4) inhibitor

Chemical Structure - P32/98, dipeptidyl peptidase IV (DPP4) inhibitor (AB141724)

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Biochemicals

AB235551

Teneligliptin, DPP-4 inhibitor

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Biochemicals

AB144783

N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neurotoxin

Chemical Structure - N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neurotoxin (AB144783)

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产品详情

This product is manufactured by BioVision, an Abcam company and was previously called 1964 DPP IV Inhibitor, NVP DPP 728. 1964-5 is the same size as the 5 mg size of ab142171.
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性能和储存信息

运输条件
Ambient - Can Ship with Ice
推荐的短期储存条件
-20°C
推荐的长期储存条件
-20°C
储存信息
Store under desiccating conditions|The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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产品实验方案

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

FEBS letters 594:2840-2866 PubMed32506501

2020

A proopiomelanocortin-derived peptide sequence enhances plasma stability of peptide drugs.

Applications

Unspecified application

Species

Unspecified reactive species

Karin Löw,Alexandre Roulin,Stefan Kunz
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Abcam Product Promise

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详情请参阅我们的条款与条件。

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