Niclosamide，STAT3抑制剂(ab120868)
Key features and details
- Antihelminthic, anticancer and protonophric agent. STAT3 inhibitor.
- CAS Number: 50-65-7
- Purity: > 95%
- Soluble in ethanol to 0.5 mg/ml
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Niclosamide，STAT3抑制剂 -
描述
Antihelminthic，anticancer and protonophric agent. STAT3抑制剂. -
纯度
> 95% -
CAS编号
50-65-7 -
化学结构
性能
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化学名称
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide -
分子量
327.12 -
分子式
C13H8Cl2N2O4 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in ethanol to 0.5 mg/ml -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
OC1=C(C(NC2=CC=C([N+]([O-])=O)C=C2Cl)=O)C=C(Cl)C=C1 -
来源
Synthetic
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研究领域
图片
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Chemical Structure - Niclosamide, STAT3 inhibitor (ab120868)2D chemical structure image of ab120868, Niclosamide, STAT3 inhibitor
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab120868 被引用在 2 文献中.
- Martinez R et al. Proteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors. ACS Omega 7:3293-3311 (2022). PubMed: 35128241
- Domfeh SA et al. Cryptolepine inhibits hepatocellular carcinoma growth through inhibiting interleukin-6/STAT3 signalling. BMC Complement Med Ther 21:161 (2021). PubMed: 34078370