Naloxone hydrochloride，Opioid拮抗剂(ab120074)
Key features and details
- Opioid antagonist
- CAS Number: 357-08-4
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
Naloxone hydrochloride，Opioid拮抗剂 -
描述
Opioid拮抗剂 -
生物学描述
Competitive opioid antagonist.
-
CAS编号
357-08-4 -
化学结构
性能
-
化学名称
(5α)-4,5-Epoxy-3,14-dihydro-17(2-propenyl)morphinan-6-one hydrochloride -
分子量
363.84 -
分子式
C19H21NO4.HCl -
PubChem识别号
5464092 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in water to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - Naloxone hydrochloride, Opioid antagonist (ab120074)2D chemical structure image of ab120074, Naloxone hydrochloride, Opioid antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (5)
ab120074 被引用在 5 文献中.
- Peters C et al. Transcriptomics reveals amygdala neuron regulation by fasting and ghrelin thereby promoting feeding. Sci Adv 9:eadf6521 (2023). PubMed: 37224253
- Liu S et al. Effect of endomorphin-2 on orofacial pain induced by orthodontic tooth movement in rats. Eur J Oral Sci 127:408-416 (2019). PubMed: 31365768
- Birdsong WT et al. Synapse-specific opioid modulation of thalamo-cortico-striatal circuits. Elife 8:N/A (2019). PubMed: 31099753
- Arttamangkul S et al. Cellular tolerance at the µ-opioid receptor is phosphorylation dependent. Elife 7:N/A (2018). PubMed: 29589831
- Charlet A et al. Abnormal nociception and opiate sensitivity of STOP null mice exhibiting elevated levels of the endogenous alkaloid morphine. Mol Pain 6:96 (2010). PubMed: 21172011