MRS 1754，A2B拮抗剂(ab120397)
Key features and details
- Selective A2B antagonist
- CAS Number: 264622-58-4
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
MRS 1754，A2B拮抗剂 -
描述
Selective A2B拮抗剂 -
生物学描述
Selective A2B antagonist (Ki values are 1.97 (hA2B), 403 (hA1), 503 (hA2A), and 570 nM (hA3)).
-
CAS编号
264622-58-4 -
化学结构
性能
-
化学名称
N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide -
分子量
486.53 -
分子式
C26H26N6O4 -
PubChem识别号
6603931 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
N#Cc1ccc(cc1)NC(=O)COc2ccc(cc2)c3nc4C(=O)N(CCC)C(=O)N(CCC)c4n3 -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - MRS 1754, A2B antagonist (ab120397)2D chemical structure image of ab120397, MRS 1754, A2B antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (3)
ab120397 被引用在 3 文献中.
- Basu M et al. Increased host ATP efflux and its conversion to extracellular adenosine is crucial for establishing Leishmania infection. J Cell Sci 133:N/A (2020). PubMed: 32079656
- Zhou Y et al. MRS1754 inhibits proliferation and migration of bladder urothelial carcinoma by regulating mitogen-activated protein kinase pathway. J Cell Physiol 234:11360-11368 (2019). PubMed: 30565699
- Yi X et al. Adenosine receptors enhance the ATP-induced odontoblastic differentiation of human dental pulp cells. Biochem Biophys Res Commun 497:850-856 (2018). PubMed: 29454963