Mirtazapine，alpha2，5-HT2，5-HT3拮抗剂(ab120068)
Key features and details
- Antidepressant. α2, 5-HT2, 5-HT3 antagonist.
- CAS Number: 85650-52-8
- Soluble in DMSO to 20 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
Mirtazapine，alpha2，5-HT2，5-HT3拮抗剂 -
描述
Antidepressant. α2，5-HT2，5-HT3拮抗剂. -
别名
- 6-Azamianserin
- Org3770
-
生物学描述
Antagonist at α2, 5-HT2 and 5-HT3 receptors. Antidepressant in vivo.
-
CAS编号
85650-52-8 -
化学结构
性能
-
化学名称
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c]benzazepine -
分子量
265.35 -
分子式
C17H19N3 -
PubChem识别号
4205 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 20 mM and in ethanol to 50 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CN1CC2N(CC1)c4ncccc4Cc3ccccc23 -
来源
Synthetic
-
研究领域
图片
-
Chemical Structure - Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist (ab120068)2D chemical structure image of ab120068, Mirtazapine, alpha2, 5-HT2, 5-HT3 antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (2)
ab120068 被引用在 2 文献中.
- Nerli E et al. In vitro modeling of dendritic atrophy in Rett syndrome: determinants for phenotypic drug screening in neurodevelopmental disorders. Sci Rep 10:2491 (2020). PubMed: 32051524
- Flores Gutiérrez J et al. Protective role of mirtazapine in adult female Mecp2+/- mice and patients with Rett syndrome. J Neurodev Disord 12:26 (2020). PubMed: 32988385