LY 456236,mGlu1 non competitive拮抗剂(ab120201)
Key features and details
- mGlu1 non competitive antagonist
- CAS Number: 338736-46-2
- Soluble in DMSO to 50 mM (with warming)
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
LY 456236,mGlu1 non competitive拮抗剂 -
描述
mGlu1 non competitive拮抗剂 -
生物学描述
Selective non-competitive antagonist at the mGlu1 receptor. Inhibits agonist induced phosphoinositide hydrolysis in vitro (IC50 = 140 nM) and in vivo following systemic administration.
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CAS编号
338736-46-2 -
化学结构
性能
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化学名称
(4-Methoxyphenyl)-(6-methoxy-quinazolin-4-yl)amine hydrochloride -
分子量
317.77 -
分子式
C16H15N3O2.HCl -
PubChem识别号
9926998 -
存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 50 mM (with warming) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.COc1ccc(cc1)Nc3ncnc2ccc(cc23)OC -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120201 尚未被引用在任何文献中。