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LCL161 (ab273616)

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Chemical Structure - LCL161 (ab273616)

    Key features and details

    • Potent IAP inhibitor
    • CAS Number: 1005342-46-0
    • Purity: > 99%

    • Soluble in DMSO to 50 mM

    • Form / State: Solid
    • Source: Synthetic

    概述

    • 产品名称

      LCL161

    • 描述

      Potent IAP 抑制剂

    • 生物学描述

      Small molecule SMAC mimetic inhibitor of multiple IAP (Inhibitor of apoptosis) family proteins.  (IC50 = 10.23 μM). Inhibits cell proliferation and viability in two human hepatocellular carcinoma cells (Hep3B,  IC50 = 10, and PLC5, IC50 = 19). 

    • 纯度

      > 99%

    • 常规说明

      For obtaining a higher solubility, please warm the tube at 37°C and shake in the ultrasonic bath for a while.

    • CAS编号

      1005342-46-0

    • 化学结构

      Chemical Structure

    性能

    • 化学名称

      (2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide

    • 分子量

      500.63

    • 分子式

      C26H33FN4O3S

    • PubChem识别号

      24737642

    • 存放说明

      Shipped at room temperature. Store at -20°C.

    • 溶解度概述

      Soluble in DMSO to 50 mM

    • 处理

      Refer to SDS for further information

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC

    • 来源

      Synthetic

    图片

    • Chemical Structure - LCL161 (ab273616)
      Chemical Structure - LCL161 (ab273616)

      Chemical structure of LCL161, 1005342-46-0

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab273616？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab273616 尚未被引用在任何文献中。

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