L-741,626，D2拮抗剂(ab120596)
Key features and details
- Potent and selective D2 antagonist
- CAS Number: 81226-60-0
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
L-741,626，D2拮抗剂 -
描述
Potent and selective D2拮抗剂 -
生物学描述
Potent and selective D2 antagonist (Ki values are 2.4, 100 and 220 nM at D2, D3 and D4 receptors, respectively). Centrally active following in vivo systemic administration.
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纯度
> 99% -
CAS编号
81226-60-0 -
化学结构
性能
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化学名称
4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol -
分子量
340.85 -
分子式
C20H21ClN2O -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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来源
Synthetic
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研究领域
图片
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Chemical Structure - L-741,626, D2 antagonist (ab120596)2D chemical structure image of ab120596, L-741,626, D2 antagonist
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120596 被引用在 1 文献中.
- Platt NJ et al. Striatal dopamine transmission is subtly modified in human A53Ta-synuclein overexpressing mice. PLoS One 7:e36397 (2012). PubMed: 22570709